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Background/Objectives: The incidence of colorectal cancer in Hungary exceeds the EU (European Union) average, and the cancer mortality rate is also among the highest in the country. The COVID-19 pandemic has impacted various areas of healthcare, including cancer diagnosis and treatment. Due to the measures taken to combat the COVID-19 pandemic, not only newly suspected cancer patients but also those already diagnosed and undergoing treatment faced numerous difficulties. Methods: The study included 198 patients with colorectal cancer, of whom 43 participants were newly diagnosed cases. Due to low case numbers in certain COVID-19 waves, adjacent waves were merged for statistical analysis. The number of newly diagnosed colorectal cancer cases across COVID-19 waves was compared using one-way ANOVA, stage distribution differences and the proportion of missed treatments were assessed with Fisher's exact test. In follow-up patients, changes were analyzed using the Wilcoxon signed-rank test. Differences in tumor size categories were examined using chi-square tests.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Colorectal cancer patients | Patients with colorectal cancer undergoing MRI examination during and after the COVID-19 pandemic. |
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| Measure | Description | Time Frame |
|---|---|---|
| Tumor stage distribution across COVID-19 pandemic waves | Comparison of colorectal cancer tumor stage (AJCC 8th edition) across different COVID-19 pandemic waves and the post-COVID period based on MRI findings. | September 2020 - December 2023 |
| Number of newly diagnosed colorectal cancer cases | Monthly number of newly diagnosed colorectal cancer cases across COVID-19 waves and the post-COVID period. | September 2020 - December 2023 |
| TNM classification | TNM classification of colorectal cancer according to the AJCC 8th edition during different COVID-19 pandemic waves in newly diagnosed and follow-up patients. | September 2020 - December 2023 |
| Measure | Description | Time Frame |
|---|---|---|
| Tumor progression or regression in follow-up patients | Change in tumor stage between previous imaging and most recent MRI examination. | September 2020 - December 2023 |
| Missed oncologic treatments |
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Inclusion Criteria:
Exclusion Criteria:
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Adult patients with colorectal cancer undergoing MRI examination during and after the COVID-19 pandemic.
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| Name | Affiliation | Role |
|---|---|---|
| József Tollár, Dr. | University of Pécs, Faculty of Health Sciences, Hungary | Principal Investigator |
| Adrienn Biró, Dr. | Somogy County Móricz Kaposi Teaching Hospital, 7400 Kaposvár, Hungary | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Szent Margit Hospital | Budapest | 1032 | Hungary |
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| ID | Term |
|---|---|
| D015179 | Colorectal Neoplasms |
| D000086382 | COVID-19 |
| ID | Term |
|---|---|
| D007414 | Intestinal Neoplasms |
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
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Occurrence of missed or delayed oncologic treatments documented during the COVID-19 pandemic period.
| September 2020 - December 2023 |
| Presence and distribution of metastases | Presence, number, and organ distribution of metastatic disease based on imaging findings. | September 2020 - December 2023 |
| D009369 | Neoplasms |
| D004066 | Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D003108 | Colonic Diseases |
| D007410 | Intestinal Diseases |
| D012002 | Rectal Diseases |
| D011024 | Pneumonia, Viral |
| D011014 | Pneumonia |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
| D014777 | Virus Diseases |
| D018352 | Coronavirus Infections |
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |