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This study investigates the effect of cognitive priming through mental arithmetic on functional mobility in post-stroke patients. It hypothesizes that performing mental calculations (addition, subtraction, multiplication) prior to movement stimulates frontoparietal networks, thereby improving gait speed and dynamic balance compared to a passive control condition.
Stroke often results in impaired sensorimotor integration and executive dysfunction, leading to gait and balance deficits. Emerging evidence suggests a link between numerical cognition and motor control networks. This randomized controlled trial compares an experimental group (performing 30-second mental arithmetic tasks) against a control group (passive visual exposure). Functional mobility is assessed immediately following the cognitive stimulus using the Ten-Meter Walk Test (10mWT) and the Timed Up and Go (TUG) test to evaluate the immediate "priming" effects of cognitive load on motor performance.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention: Behavioral: Mental Arithmetic | Experimental | Visual presentation of arithmetic equations (Addition, Subtraction, Multiplication) projected on a screen. Participants must calculate and verbally report the answer within a 10-second window per equation. |
|
| Passive Viewing | Placebo Comparator | Passive viewing of a black screen with no cognitive demand. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Mental Arithmetic | Behavioral | Visual presentation of arithmetic equations (Addition, Subtraction, Multiplication) projected on a screen. Participants must calculate and verbally report the answer within a 10-second window per equation. |
| Measure | Description | Time Frame |
|---|---|---|
| Gait Speed (10mWT) | Assessed using the Ten-Meter Walk Test (10mWT). Participants walk 14 meters; time is recorded for the middle 10 meters to determine steady-state gait speed. | Immediately following the 30-second cognitive stimulus. |
| Dynamic Balance (TUG) | Assessed using the Timed Up and Go (TUG) test. Time taken to stand from a chair, walk 3 meters, turn, walk back, and sit down. | Immediately following the 30-second cognitive stimulus. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ahmad I. Rifai Sarraj, PhD | Contact | +9613662956 | ahmadrifaisarraj@ul.edu.lb | |
| Jihan Allaw, Master | Contact | jihan.allaw.1@ul.edu.lb |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31146193 | Background | Khayat J, Champely S, Diab A, Rifai Sarraj A, Fargier P. Effect of mental calculus on the performance of complex movements. Hum Mov Sci. 2019 Aug;66:347-354. doi: 10.1016/j.humov.2019.05.008. Epub 2019 May 28. No abstract available. |
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Individual participant data (IPD) that underlie the results reported in this article (after de-identification) will be shared. This includes the data used to generate the tables and figures.
Data will be available beginning 6 months and ending 5 years following article publication.
Data will be shared with researchers who provide a methodologically sound proposal to the corresponding author. Proposals should be directed to ahmadrifaisarraj@ul.edu.lb. To gain access, data requestors will need to sign a data access agreement.
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| ID | Term |
|---|---|
| D020521 | Stroke |
| D010291 | Paresis |
| D051346 | Mobility Limitation |
| D004194 | Disease |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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Single Blind (Participant)
| Passive Viewing | Behavioral | Passive viewing of a black screen with no cognitive demand. |
|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010335 | Pathologic Processes |