Efficacy and Safety of Non-Invasive Brain-Computer Interface Combined With Transcranial Electrical Stimulation in the Treatment of Peripheral Facial Palsy
Efficacy and Safety of Non-Invasive Brain-Computer Interface Combined With Transcranial Electrical Stimulation in the Treatment of Peripheral Facial Palsy
To evaluate the efficacy and safety of treating peripheral facial palsy using a non-invasive brain-computer interface combined with transcranial direct current stimulation (tDCS).
This study is mainly designed to compare the therapeutic efficacy of non-invasive brain-computer interface combined with transcranial direct current stimulation (tDCS), pulsed radiofrequency, and pharmacological treatment versus pulsed radiofrequency combined with pharmacological treatment in patients with peripheral facial palsy.
Inclusion Criteria:
Aged 18-70 years, regardless of sex.
Unilateral peripheral facial nerve palsy.
House-Brackmann (HB) grade II-VI.
Able to cooperate with target facial movement tasks and provide written informed consent, with intact cognitive function and good communication ability.
Good skin condition, with no severe skin lesions or facial skin grafts; no implanted electronic devices such as cardiac pacemakers or deep brain stimulators, to avoid electrophysiological interference.
Non-pregnant and non-lactating women, in accordance with regulatory requirements for minimal-risk research.
Exclusion Criteria:
Open facial wounds, active infections, significant skin lesions, or a history of severe allergy.
Severe cognitive impairment, psychiatric disorders, or inability to comply with study procedures.
Occurrence of serious adverse events or withdrawal at the patient's request.
Pregnant or lactating women, or patients unable to use appropriate contraceptive measures during the study period.