This study is to evaluate the efficacy and safety of Meropenem and Pralurbactam for Injection in Subjects with HABP/VABP. The primary objective is to demonstrate non-inferiority of Meropenem and Pralurbactam to Ceftazidime and Avibactam Sodium for Injection. This study is a randomized, double-blind, active-controlled study. The total duration of the study will be approximately 32 days including screening and follow-up.

Inclusion Criteria:

• 1. Male or female participants ≥18 and ≤80 years of age

  2. have a diagnosis of HAP/VAP.

  3. have systemic signs and respiratory signs or symptoms of HAP/VAP.

  4. New or worsening infiltrate on chest X-ray/CT obtained within 48 hours prior to screening.

  5. The estimated survival time is at lest 28 days.

Exclusion Criteria:

• 1. Diagnosed or suspected CAP, Atypical pneumonias, Viral pneumonia or Chemical pneumonia.

  2. The total duration of antibiotic exposure for antibiotics whose administration begins in the 72 hours is longer than 24 hours.

  3. Acute Physiology and Chronic Health Evaluation (APACHE) II score >30.

  4. Allergic to any carbapenem, cephalosporin, penicillin, metronidazole disodium phosphate, other beta-lactam drugs or other beta-lactamase inhibitors and their auxiliary materials.

  5. Those who have a history of drug abuse or drug abuse within 6 months before screening.

  6. Those who participated in other clinical trials within 28 days before randomization and used any test drugs or medical devices.