"Artificial intelligence (AI), including large language models and conversational tools, is increasingly being used in medical research. These tools may assist researchers at different stages of the scientific process, such as generating research ideas, reviewing the literature, analyzing data, writing manuscripts, and preparing articles for publication. While interest in AI is growing rapidly, there is still limited information on how these tools are actually perceived and used by leading medical researchers. This study aims to better understand the attitudes, perceptions, and self-reported uses of artificial intelligence among corresponding authors who have published in six major international medical journals. These authors play a key role in shaping scientific standards and editorial practices, and their views are essential to understanding how AI may influence the future of medical research. Participants are invited to complete an anonymous online questionnaire that asks about their familiarity with AI tools, how and when they use or plan to use them in the research process, the potential benefits they perceive, and the concerns or limitations they identify. The survey also explores participants' expectations regarding transparency, ethical guidance, and journal policies related to the use of artificial intelligence in scientific work.The study is observational and does not involve any medical intervention or collection of personal or health-related data. Participation is voluntary, and responses are fully anonymous.

Inclusion Criteria:

• Participants without any disease, condition, or related symptoms are permitted to participate. This study is a non-clinical, observational survey focusing on attitudes and practices related to artificial intelligence in scientific research, not on health conditions.

Exclusion Criteria:

• Authors who are not corresponding authors.
• Students, residents, interns, or trainees without corresponding author status.
• Individuals not involved in biomedical or medical research activities.
• Individuals who decline to participate or do not complete the online questionnaire.

The study population consists of corresponding authors who have published scientific articles in leading international medical journals. Participants are identified through publicly available publication data from six major journals (The New England Journal of Medicine, The Lancet, JAMA, Nature, Science, and The BMJ) and are invited to participate via professional email addresses. The population includes adult researchers from diverse biomedical and medical disciplines, with no geographic restriction.