Retrospective Evaluation of the Long-term Effectiveness of the CR500™ SINGLE-DOSE GEL Medical Device in Patients With Knee Osteoarthritis (KOA)

Retrospective Evaluation of the Long-term Effectiveness of the CR500™ SINGLE-DOSE GEL Medical Device in Patients With Knee Osteoarthritis (KOA) Enrolled in the Clinical Study CTD-SW CR500™-KOA 2020

Evaluate the long-term efficacy of the CR500™ therapy in patients with knee OA.

To assess whether and when the patients enrolled in the CTD-SW CR500™-KOA 2020 clinical study required new orthopaedic treatment for knee osteoarthritis, starting at least 24 months after the conclusion of the clinical study.

Evaluate whether, in the long term, despite the potential bias of other therapies, treatment with CR500 has led to a lasting improvement, especially in comparison with infiltrative treatments based on the literature.

Collect data on patient satisfaction with the therapy received

Inclusion Criteria:

• Oral informed consent from the patient.
• Participation in the CTD-SW CR500™-KOA 2020 clinical study.
• Willingness to participate in the survey.

Exclusion Criteria:

• Patients who were excluded following major protocol violations during the CTD-SW CR500™-KOA 2020 clinical study