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| ID | Type | Description | Link |
|---|---|---|---|
| 2025-A00957-42 | Other Identifier | ANSM |
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Modern lifestyles are marked by a prevalence of sedentary behaviors and physical inactivity, which have been linked to numerous adverse health effects. While regular physical exercise is a well-established countermeasure, exercising in the late afternoon may paradoxically disrupt deep sleep due to increased core body temperature. Inactive and sedentary individuals, who often have impaired autonomic function compared to endurance-trained athletes, may be particularly susceptible to these negative effects, potentially resulting in compromised thermoregulation and exacerbated disruptions to deep sleep, a critical stage of sleep essential for overall recovery. Therefore, this study aims to investigate the impact of aerobic exercise performed in the late afternoon versus morning on: 1) deep sleep and sleep onset latency; and 2) core body temperature and its autonomic regulatory mechanisms on endurance-trained and inactive-sedentary people.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| "Inactive-sedentary" group | Active Comparator | inactive participants that realize 3 experimental conditions: evening exercise, morning exercise and control (no-exercise). |
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| "Active" group | Experimental | endurance athletes that realize 3 experimental conditions: evening exercise, morning exercise and control (no-exercise). |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Aerobic Exercise | Other | The exercise consists of running on a treadmill at 90% of maximum aerobic speed (MAS) for 30 minutes, followed by 12% increments every 5 minutes, until exhaustion (a "time-to-exhaustion" type of exercise). |
| Measure | Description | Time Frame |
|---|---|---|
| Duration of deep slow-wave sleep | Evaluation of the duration of deep slow-wave sleep (N3 stage) quantified by the EEG signal from polysomnography (Nox A1, Resmed®, USA). | Once a month for 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Assessment of core temperature | Assessment of core temperature until the end of the sleep period will be measured using gastrointestinal telemetric pills (eCelsius, Bodycap®, France). | Once a month for 3 months |
| Evaluation of autonomic nervous system thermoregulation |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Frédéric ROCHE, PhD | Contact | 0477828695 | 33 | frederic.roche@univ-st-etienne.fr |
| Name | Affiliation | Role |
|---|---|---|
| Frédéric ROCHE, PhD | Centre Hospitalier Universitaire de Saint Etienne | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Chu Saint-Etienne | Recruiting | Saint-Etienne | 42055 | France |
This study is realized only in St-Etienne university Hospital
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| ID | Term |
|---|---|
| D007319 | Sleep Initiation and Maintenance Disorders |
| ID | Term |
|---|---|
| D020919 | Sleep Disorders, Intrinsic |
| D020920 | Dyssomnias |
| D012893 | Sleep Wake Disorders |
| D009422 | Nervous System Diseases |
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| ID | Term |
|---|---|
| D015444 | Exercise |
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
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This is a single-center, open-label, randomized controlled trial with two parallel crossover groups:
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Evaluation of autonomic nervous system thermoregulation through time-domain (R-R intervals in ms) |
| Once a month for 3 months |
| Evaluation of autonomic nervous system thermoregulation | Evaluation of autonomic nervous system thermoregulation through frequency- domain parameters (in Hz) | Once a month for 3 months |
| Complementary sleep evaluation | Complementary sleep evaluation through analysis of duration of N1, N2, and REM stages (in Percentage of Total Sleep Time) | Once a month for 3 months |
| Complementary sleep evaluation | Complementary sleep evaluation through characteristics of slow waves present in N3 (amplitude in microvolts) | Once a month for 3 months |
| D001523 |
| Mental Disorders |