Ultrasound-Guided PASC Block vs Femoral-Sciatic Nerve Block for Postoperative Analgesia After Total Knee Arthroplasty

Postoperative Analgesic Efficacy of Ultrasound Guided Para-sartorial Compartments (PASC) Block Versus Combined Femoral-Sciatic Nerve Block in Patients Undergoing Total Knee Arthroplasty: A Double-Blind Randomized Comparative Study

This randomized, double-blind comparative study evaluates postoperative analgesic efficacy and motor effects of ultrasound-guided para-sartorial compartments (PASC) block versus ultrasound-guided combined femoral-sciatic nerve block in patients undergoing total knee arthroplasty. The primary endpoint is total nalbuphine rescue analgesia consumption in the first 24 postoperative hours. Secondary endpoints include pain scores (NRS), motor function using a modified Bromage scale, block performance characteristics, and complications.

Inclusion Criteria:

• Age 60 to 70 years
• Scheduled for elective total knee arthroplasty under general anesthesia
• American Society of Anesthesiologists physical status class I or II
• Provided written informed consent

Exclusion Criteria:

• American Society of Anesthesiologists physical status class III or IV
• Pre-existing neurological abnormality of the lower extremity
• Infection near the planned block site
• History of psychiatric illness
• History of drug abuse
• Known allergy to local anesthetics or any study medications (bupivacaine, acetaminophen, ketorolac, nalbuphine)