Efficacy And Safety Of Azithromycin To Achieve Remissionin In Children With Steroid Sensitive Nephrotic Syndrome

Efficacy And Safety Of Azithromycin To Achieve Remissionin In Children With Steroid Sensitive Nephrotic Syndrome

To compare efficacy and safety of Azithromycin versus control in children with steroid sensitive nephrotic syndrome

It is a randomized controlled trial. Total 160 children meeting inclusion criteria will be included in the study. Selected children will be divided into 2 groups. one group will be given Azithromycin at 10mg/kg/day (1 dose per day) for 3 days along with standard course of steroids. 2nd group will be given standard course of treatment. All patients will be followed up for 1 month and remission will be noted. All data will be collected through specially designed performa. Patient's safety and Efficacy of drug in Achieving early Remission will be closely monitored.

Inclusion Criteria:

• Children age 2 to 14 years
• Both genders
• Children having primary nephrotic syndrome

Exclusion Criteria:

• Children with steroid resistant nephrotic syndrome
• Children with secondary causes of nephrotic syndrome
• Recent use of azithromycin during last 4 weeks
• Severe systemic infection requiring antibiotics
• Chronic liver disease Prolong QT Interval or history of cardiac arythmias