Ozonated Gel and Titanium Platelet-rich Fibrin (on Palatal Wound Healing

Comparison of Topically Applied Ozonated Gel and Titanium Platelet-rich Fibrin (Tprf) on Palatal Wound Healing (A Randomized Controlled Clinical Trial)

Background: autogenous soft tissue grafts can be considered the gold standard for treatment of mucogingival problems. The most common site for harvesting the graft is the palate. The palatal donor site for free gingival graft (FGG) significantly influences the pain and discomfort experienced by the patient, and there is a potential for postoperative bleeding.To overcome these problems many dressing materials associated with topical formulae have been used.

Aim: The objective of this study is to assess the effect of topically applied ozonated oil on palatal wound healing and compare it to the effect of titanium platelet rich fibrin (TPRF)

Inclusion Criteria:

• Isolated gingival recession defects on the mandibular and maxillary anterior teeth with insufficient keratinized gingiva.
• Good oral hygiene

Exclusion Criteria:

• Patients reporting systemic conditions that may compromise healing or bone metabolism
• Patients having a history of radiotherapy, chemotherapy or bisphosphonate therapy.
• Pregnant women or those planning to get pregnant during the study course
• History of periodontal disease or previous periodontal surgery on the experimental sites
• Smoking or any other deleterious habits.