Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
A single blind randomized controlled clinical study
A single blind randomized controlled clinical study
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| formulation arm | Experimental | new formulation of ketoprofen |
|
| commercial product | Active Comparator | positive control receiving commercial product |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ketoprofen | Drug | new gel formulation |
| |
| ketoprofen |
| Measure | Description | Time Frame |
|---|---|---|
| Visual Analogue Scale (VAS) | 2 weeks | |
| McMaster Universities Arthritis Index (WOMAC) | 2 weeks |
Not provided
Not provided
Inclusion Criteria:
Full history taking Physical examination including (joint tenderness, swelling, crepitus and limitation of motion).
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Sara A Hassan | Badr University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Minia University | Minya | Minya Governorate | 11666 | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36086745 | Background | Wang Y, Fan M, Wang H, You Y, Wei C, Liu M, Luo A, Xu X, Duan X. Relative safety and efficacy of topical and oral NSAIDs in the treatment of osteoarthritis: A systematic review and meta-analysis. Medicine (Baltimore). 2022 Sep 9;101(36):e30354. doi: 10.1097/MD.0000000000030354. |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D020370 | Osteoarthritis, Knee |
| ID | Term |
|---|---|
| D010003 | Osteoarthritis |
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
Not provided
Not provided
| ID | Term |
|---|---|
| D007660 | Ketoprofen |
| ID | Term |
|---|---|
| D010666 | Phenylpropionates |
| D000146 | Acids, Carbocyclic |
| D002264 | Carboxylic Acids |
| D009930 | Organic Chemicals |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Drug |
commercial gel |
|
| D012216 |
| Rheumatic Diseases |