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This study aimed to assess and compare predictors of outcome in patients with thymomatous and non-thymomatous MG undergoing Thoracoscopic thymectomy.
Myasthenia Gravis (MG) is a chronic autoimmune neuromuscular disorder characterized by fluctuating muscle weakness resulting from antibodies that target acetylcholine receptors or associated proteins at the neuromuscular junction.
Thoracoscopic thymectomy becomes more prominent than traditional transsternal thymectomy due to fewer perioperative complications with shorter hospital stays and more favorable long-term outcomes.
Prognostic outcomes following thoracoscopic thymectomy can vary significantly between non-thymomatous and thymomatous MG, necessitating a thorough investigation of these differences.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Thymomatous Myasthenia Gravis group | Thymomatous myasthenia gravis (patients with histologically confirmed thymoma). |
| |
| Non-thymomatous Myasthenia Gravis group | Non-thymomatous myasthenia gravis (patients with thymic hyperplasia or normal/ involuted thymus). |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Data collection | Other | Data were obtained from patient files, operative notes, and electronic medical records. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Proportion of patients achieving complete stable remission | Proportion of patients achieving complete stable remission was recorded. | 12 months post-procedure |
| Measure | Description | Time Frame |
|---|---|---|
| Proportion of patients achieving pharmacologic remission | Proportion of patients achieving pharmacologic remission was recorded. | 12 months post-procedure |
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Inclusion Criteria:
Exclusion Criteria:
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This study was a combined prospective and retrospective, observational, and comparative study conducted in the neurology and cardiothoracic departments at Tanta and Zagazig University Hospitals between January 2022 and December 2025.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Tanta University | Tanta | El-Gharbia | 31527 | Egypt |
The data will be available upon a reasonable request from the corresponding author after the end of study for one year.
After the end of study for one year.
The data will be available upon a reasonable request from the corresponding author.
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| ID | Term |
|---|---|
| D009157 | Myasthenia Gravis |
| ID | Term |
|---|---|
| D020361 | Paraneoplastic Syndromes, Nervous System |
| D009423 | Nervous System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D010257 | Paraneoplastic Syndromes |
| D020274 | Autoimmune Diseases of the Nervous System |
| D009422 | Nervous System Diseases |
| D019636 | Neurodegenerative Diseases |
| D020511 | Neuromuscular Junction Diseases |
| D009468 | Neuromuscular Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
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| ID | Term |
|---|---|
| D003625 | Data Collection |
| ID | Term |
|---|---|
| D004812 | Epidemiologic Methods |
| D008919 | Investigative Techniques |
| D017531 | Health Care Evaluation Mechanisms |
| D011787 | Quality of Health Care |
| D017530 | Health Care Quality, Access, and Evaluation |
| D011634 | Public Health |
| D004778 | Environment and Public Health |
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