The primary aim of this double-blind randomized controlled trial is to evaluate the effectiveness of an accelerated rehabilitation protocol on knee joint function and quality of life in individuals undergoing TKA compared to conventional rehabilitation in Dali, Yunan, China. The study will include patients aged 50-80 years who are scheduled for primary unilateral TKA. Participants will be randomly assigned to either an accelerated rehabilitation group or conventional rehabilitation group. The primary outcomes will include knee joint function, assessed using the KOOS and quality of life measures using the SF-36 surveys. The study will follow participants for 6 months post-surgery to assess longer-term outcomes. This study will not include individuals undergoing revision TKA or those with severe comorbid conditions. The results will provide critical insights into the role of accelerated rehabilitation in improving post-operative recovery, functional outcomes, and overall quality of life for TKA patients.

Inclusion Criteria:

• Patients diagnosed with end-stage knee OA necessitating primary unilateral TKA.

Exclusion Criteria:

• History of joint infections, cancer, or inflammatory arthritis.
• End-stage OA from rheumatoid or septic arthritis.
• Individuals with neurological disorders such as Alzheimer's disease, - Parkinson's disease, stroke.
• Individuals who are unable to follow a structured rehabilitation protocol.
• Previous history of knee surgeries (other than arthroscopy).
• Severe comorbidities that would hinder participation (e.g., advanced cardiovascular diseases).
• Individuals who have severe osteoporosis.