Topical Use of 2% Tofacitinib for Nail Psoriasis: an Exploratory Clinical Study

Topical Use of 2% Tofacitinib for Nail Psoriasis: an Exploratory Clinical Study

To evaluate the efficacy and safety of topical 2% tofacitinib nail lacquer in nail psoriasis, using the NAPSI and DLQI scales before and after 26 weeks of treatment.

Inclusion Criteria: Age ≥ 18 years;

• Presence of nail psoriasis in at least one fingernail or toenail;
• Patients not using systemic medication, or without adequate response to systemic medication after at least 6 months of use;
• Ability to read, understand, and sign the Informed Consent Form (ICF) and the Consent Form for Images, Presentations, and Scientific Publications.

Exclusion Criteria: Pregnant or breastfeeding women or those planning to become pregnant during the study period;

• History of sensitivity to any components of the study product;
• Initiation of systemic medication for nail psoriasis less than six months prior.