Analysis of NfL and GFAP in Different Dietary Patterns | NCT07312994

Studies
Analysis of NfL and GFAP in Different Dietary Patterns

NCT07312994

Sponsor

Salzburger Landeskliniken

Status

Recruiting

Last Update Posted

Dec 31, 2025Actual

Enrollment

300Estimated

Phase

Not provided

Conditions

Neurofilament Light Chain
Glial Fibrillary Acidic Protein
GFAP
Vegan Diet
Vegetarian Diet

Interventions

Not provided

Countries

Austria

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Dec 2025

Overall Recruitment Status or Expanded Access Status

Recruiting

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Dec 18, 2025Actual

Primary Completion Date

Apr 2026Estimated

Completion Date

Sep 2026Estimated

First Submitted Date

Dec 9, 2025

First Submission Date that Met QC Criteria

Dec 17, 2025

First Posted Date

Dec 31, 2025Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Dec 17, 2025

Last Update Posted Date

Dec 31, 2025Actual

Sponsor/Collaborators Module

Responsible Party, by Official Title

Tobias Moser, apl. Prof., Salzburger LandesklinikenPrincipal Investigator

Lead Sponsor

Salzburger LandesklinikenOTHER

Collaborators

Name	Class
Medizinische Einrichtungen der Universität Düsseldorf	UNKNOWN
Medizinische Fakultät der Universität zu Köln	UNKNOWN
Universitätsklinkum Münster - Medizinische Klinik und Poliklinik B	OTHER

Oversight Module

Has Data Monitoring Committee (DMC)

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Description Module

Brief Summary

This observational study aims to investigate the impact of different dietary patterns on brain tissue biomarkers in healthy young adults by measuring blood levels of NfL and GFAP.

The primary research question is: Do vegan, vegetarian, or omnivorous diets influence NfL and GFAP levels?

Detailed Description

Not provided

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

Retention

Enrollment

300Estimated

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Blood levels of the following biomarkers: neurofilament light chain (NfL) in pg/mL, glial fibrillary acidic protein (GFAP) in pg/mL.		Once at baseline

Secondary Outcomes

Not provided

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

Healthy individuals who have followed a vegan, vegetarian, or omnivorous diet for at least one consecutive year
Aged between 18 and 40 years
Provision of written informed consent

Exclusion Criteria:

Diagnose neurological disorders (e.g. neurodegenerative, inflammatory, autoimmune, infectious, vascular)
Eating disorders
Excessive alcohol consumption
Pregnancy
Recent moderate to severe infection (within the past 12 weeks) , including SARS-CoV-2
Recent trauma, injury, or surgery (within the past 12 weeks)
Significant BMI fluctuations (>5 points) within the last year
Patients who have been using Proton pump inhibitors (PPIs) for an extended period (e.g., 1 month).

Accepts Healthy Volunteers

Yes

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

18 Years

Maximum Age

40 Years

Standard Ages

Adult

Study Population

Young and healthy individuals aged between 18 and 40 years

Sampling Method

Non-Probability Sample

Contacts/Locations Module

Central Contacts

Name	Role	Phone	Extension	Email
Tobias Moser, Prof.	Contact	+435725534720		t.moser@salk.at

Overall Officials

Not provided

Locations

Facility	Status	City	State	ZIP	Country	Contacts
Christian-Doppler-Klinik	Recruiting	Salzburg	State of Salzburg	5020	Austria

IPD Sharing Statement Module

Plan to Share IPD

Description

Not provided

Types

Not provided

Time Frame

Not provided

Access Criteria

Not provided

URL

Not provided

Condition Browse Module

MeSH Terms

ID	Term
C537987	Charcot-Marie-Tooth disease, Type 1F

Ancestor Terms

Not provided

Browse Leaves

Not provided

Browse Branches

Not provided

Label	Type	Description	Intervention Names
Omnivore
Vegan
Vegetarian