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| ID | Type | Description | Link |
|---|---|---|---|
| NCI-2024-03737 | Registry Identifier | CTRP (Clinical Trial Reporting Program) | |
| 19PS-21-7 | Other Identifier | USC / Norris Comprehensive Cancer Center | |
| K23MD016963 | U.S. NIH Grant/Contract | View source | |
| P30CA014089 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Cancer Institute (NCI) | NIH |
| National Institute on Minority Health and Health Disparities (NIMHD) | NIH |
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This study evaluates barriers to early detection of liver cancer.
PRIMARY OBJECTIVES:
I. To identify individual-level social and clinical determinants of socioeconomic disparities in late stage Hepatocellular Carcinoma (HCC) burden with a prospective survey of patients with incident HCC. II. To qualitatively explore the multilevel barriers to completion of the early detection pathway for HCC in low socioeconomic status (SES) populations.
OUTLINE: This is an observational study.
Participants complete surveys, have their medical records reviewed, and may complete an interview on study.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Observational | Participants complete surveys, have their medical records reviewed, and may complete an interview on study. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Non-Interventional Study | Other | Non-interventional study |
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| Measure | Description | Time Frame |
|---|---|---|
| Social determinants of health | Patient social determinants of health-related needs will be measured through a health questionnaire created for the study. The patient can respond yes or no to having a lack of transportation to and from appointments. The patient is given a scale of never true, sometimes true and often true for questions regarding food insecurity. The patient can indicate that they do or do not have housing today (or choose not to answer), and they can indicate how many times they moved in the last year as 0, 1, or 2+. For the remaining questions regarding housing, paying for utilities, paying for medications, unemployment, education and child or family care, the patient can respond yes, no or choose not to answer. Responses of yes indicate the patient has a need, and no indicates that they do not have a need. | Up to 4 years |
| Barriers to completion of the early detection pathway for liver cancer | For assessment we will conduct semi-structured interviews with key stakeholders, including low-income patients with liver cancer, providers in an interconnected safety net system, and community leaders of hotspot neighborhoods. | Up to 4 years |
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Inclusion Criteria:
* Adults (18+)
Additional criteria:
Exclusion Criteria:
* Residence outside of Los Angeles County
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Patients (18+ years of age) of all stages with a diagnosis of HCC defined by guideline-based radiographic findings on cross-sectional imaging and/or histopathology
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Kali Zhou | Contact | 323-865-0451 | kalizhou@usc.edu |
| Name | Affiliation | Role |
|---|---|---|
| Kali Zhou | University of Southern California | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| USC / Norris Comprehensive Cancer Center | Recruiting | Los Angeles | California | 90033 | United States |
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| ID | Term |
|---|---|
| D006528 | Carcinoma, Hepatocellular |
| ID | Term |
|---|---|
| D000230 | Adenocarcinoma |
| D002277 | Carcinoma |
| D009375 | Neoplasms, Glandular and Epithelial |
| D009370 | Neoplasms by Histologic Type |
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| D009369 | Neoplasms |
| D008113 | Liver Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D004066 | Digestive System Diseases |
| D008107 | Liver Diseases |