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Cancer treatments, despite their increasing effectiveness, carry a significant risk of gamete toxicity.
Women of reproductive age are commonly offered fertility preservation (FP) before starting their treatment.
However, few studies have analyzed the long-term reproductive outcomes of these interventions, nor how patients ultimately use or do not use the FP options once in remission.
This project aims to better understand the effectiveness, utilization, and psychological impacts of these strategies.
This work is part of an effort to understand and evaluate fertility preservation practices implemented for women of reproductive age undergoing cancer treatment at the Amiens-Picardie University Hospital (CHU).
Its objective is to document patient pathways, clinical decisions, techniques employed, and reproductive outcomes observed after remission, in order to identify potential areas for improvement in the support and follow-up of these patients, thereby enhancing the overall quality and coordination of care.
This work is conducted alongside the development of a fertility observatory at the Department of Medicine and Reproductive Biology, CHU Amiens-Picardie.
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| Measure | Description | Time Frame |
|---|---|---|
| Occurrence of an identifiable reproductive outcome | Identifiable reproductive outcome are Spontaneous pregnancy, Use of preserved gametes or ovarian tissue (whether or not resulting in pregnancy), Use of donor oocytes, Discontinuation of the parenthood project | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Type of fertility preservation method performed | 1 year | |
| Time interval (in months) between diagnosis and fertility preservation | 1 year | |
| Correlation between Age and occurance of an identifiable reproductive outcome |
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Inclusion Criteria:
Exclusion Criteria:
Patients are recruited during follow-up consultations as part of the establishment of a fertility observatory within the Department of Medicine and Reproductive Biology at CHU Amiens Picardie
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| CABRY-GOUBET Rosalie, Pr | Contact | 33+3 22 08 80 00 | cabry.rosalie@chu-amiens.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU Amiens Picardie | Recruiting | Amiens | France |
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Identifiable reproductive outcome are Spontaneous pregnancy, Use of preserved gametes or ovarian tissue (whether or not resulting in pregnancy), Use of donor oocytes, Discontinuation of the parenthood project |
| 1 year |
| Time interval (in months) between fertility preservation and initiation of potentially gonadotoxic treatment | 1 year |
| Number of type of cancer associated with identifiable reproductive outcome | Identifiable reproductive outcome are Spontaneous pregnancy, Use of preserved gametes or ovarian tissue (whether or not resulting in pregnancy), Use of donor oocytes, Discontinuation of the parenthood project | 1 year |
| Correlation between type of treatment and occurence of an identifiable reproductive outcome | Identifiable reproductive outcome are Spontaneous pregnancy, Use of preserved gametes or ovarian tissue (whether or not resulting in pregnancy), Use of donor oocytes, Discontinuation of the parenthood project | 1 year |
| Correlation between family status and occurence of an identifiable reproductive outcome | Identifiable reproductive outcome are Spontaneous pregnancy, Use of preserved gametes or ovarian tissue (whether or not resulting in pregnancy), Use of donor oocytes, Discontinuation of the parenthood project | 1 year |
| Time interval (in months) between completion of treatment and pregnancy attempt (spontaneous or medically assisted) | 1 year |
| Actual utilization rate of preserved material | 1 year |
| Success rate of reuse attempts | 1 year |
| Proportion of patients who ultimately did not pursue parenthood | 1 year |
| ID | Term |
|---|---|
| D009369 | Neoplasms |
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