Impact of Vascular Resection on Survival and Postoperative Outcomes in Patients With Hilar Cholangiocarcinoma: A Retrospective Study

Impact of Vascular Resection on Survival and Postoperative Outcomes in Patients With Hilar Cholangiocarcinoma: A Retrospective Study

Hilar cholangiocarcinoma is a highly aggressive malignancy, and surgical resection remains the only potentially curative treatment. Due to the frequent involvement of major vascular structures, vascular resection is increasingly performed to achieve negative surgical margins; however, its impact on survival and postoperative outcomes remains controversial. This retrospective study aims to evaluate the association between vascular resection and clinical outcomes, including survival and postoperative outcomes, in patients with hilar cholangiocarcinoma undergoing curative-intent surgery.

Inclusion Criteria:

• Patients who underwent surgical treatment at the Department of Hepatobiliary and Pancreatic Surgery of our hospital between January 2010 and December 2024, including those with or without concomitant vascular resection.
• Pathologically confirmed diagnosis of hilar cholangiocarcinoma after surgery.
• Complete clinical and follow-up data available for outcome analysis.

Exclusion Criteria:

• Patients with distant metastasis or who underwent only palliative or exploratory surgery.
• Patients diagnosed preoperatively or intraoperatively with other types of biliary malignancies not located at the hilar region.
• Patients with incomplete medical records or missing key clinical or follow-up data.