Blood Flow Restriction Training (BFR) is a technique applied using a cuff or tourniquet to restrict venous return while maintaining arterial blood flow during exercise. In recent years, BFR has gained increasing attention as an effective method to enhance muscle activity with low-intensity training. This study aims to evaluate the acute effects of BFR training on a relatively underexplored area-balance and proprioception-and to analyze these effects by comparing them with sham and control groups.

The study is planned to include healthy individuals aged 18-35 years. Participants will be divided into three groups: BFR, sham, and control. Before and after the exercise protocol, all participants' demographic information and physical activity levels will be recorded. In the next phase, participants will undergo assessments of static and dynamic balance, knee and ankle proprioception measurements, and single-leg hop tests. After completing a single-session exercise protocol, all assessment tests will be repeated for each participant. The collected data will be compared across groups.

The expected outcome of the study is that the BFR group, in which arterial occlusion will be applied, will show significant improvements in parameters related to balance and proprioception compared to the other groups.

The novelty of this study lies in examining both the effects of BFR on balance and proprioception and their acute-level manifestations. Currently, studies investigating the effects of BFR on balance and proprioception are limited. Our study aims not only to contribute to the diversity of literature on balance exercise applications but also, if the acute effects of BFR are confirmed, to provide a new perspective on the application of this exercise method in physiotherapy, rehabilitation, and sports sciences.

Blood Flow Restriction Exercise (BFR) has emerged as a highly effective method for enhancing muscle activity through low-intensity training, typically performed at 20-30% of one-repetition maximum. The technique involves the application of an external constrictive device, such as a cuff or tourniquet, which limits venous return while maintaining arterial blood flow. This creates a localized hypoxic environment in the distal musculature, leading to metabolic stress that is thought to activate group III and IV afferent nerve fibers. These fibers, in turn, recruit fast-twitch motor units that are particularly responsive to hypertrophic adaptations and may stimulate anabolic hormone release. Evidence from resistance training studies indicates that BFR can enhance muscle protein synthesis, increase muscle cross-sectional area, and preferentially activate type II fibers even at low exercise intensities. Furthermore, BFR combined with aerobic exercise has been shown to improve cardiovascular endurance, maximal oxygen uptake, and metabolic adaptations, suggesting its versatility across different training modalities and populations.

Despite extensive research on BFR's effects on muscle strength and hypertrophy, its influence on balance and proprioception remains relatively unexplored. Proprioception, which enables the perception of body position and movement through interactions between the musculoskeletal and central nervous systems, is essential for postural control, motor coordination, injury prevention, and safe performance of daily and athletic activities. Postural stability depends on the integration of vestibular, visual, and proprioceptive inputs, with muscle stiffness and reflexive responses playing crucial roles. Temporary restriction of blood flow during BFR may modulate sensory feedback from mechanoreceptors, such as muscle spindles and Golgi tendon organs, potentially enhancing proprioceptive acuity and postural control. Activation of group III and IV afferents, which convey mechanical, metabolic, and nociceptive signals to the central nervous system, is considered a key mechanism underlying these effects. Group III afferents are primarily sensitive to mechanical stimuli such as tension and intramuscular pressure, while group IV afferents respond predominantly to metabolic changes. By stimulating these afferent pathways, BFR may facilitate short-term neuromuscular adaptations that improve both balance and proprioception.

Although some studies have reported improvements in postural control and static balance parameters following BFR, the literature remains limited and occasionally inconsistent. There is a particular scarcity of research investigating the acute effects of BFR on proprioception and balance in young sedentary adults, as most prior studies have focused on strength, hypertrophy, or aerobic performance. The present study aims to fill this gap by evaluating the immediate neuromuscular responses to a single session of BFR exercise, with a focus on proprioceptive function and postural stability. Findings from this research are expected to provide novel insights into the application of BFR for rehabilitation, injury prevention, and athletic performance optimization, offering evidence-based guidance for exercise prescription in both clinical and sporting populations.

Inclusion Criteria:

• Be male or female between 18 and 35 years of age.
• Have a physical activity level defined as an energy expenditure of at least 600 MET-minutes per week, according to the International Physical Activity -Questionnaire - Short Form (IPAQ-SF).
• Have normal knee joint range of motion (flexion: 0-135°; hyperextension: 0-10°).
• Have normal ankle joint range of motion (dorsiflexion: 0-20°; plantarflexion: 0-45°).

Exclusion Criteria:

• History of low back or lower extremity injury within the past 6 months.
• History of neurological or vestibular disorders.
• History of lower extremity surgery.
• Risk factors for deep vein thrombosis.
• Presence of at least one contraindication preventing participation in exercises involving blood flow restriction (e.g., smoking, previous venous thromboembolism, peripheral vascular disease risk such as ankle-brachial index <0.9, coronary heart disease, hypertension, hemophilia, etc.).

18.02.2026 - 18.02.2027