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-To measure SUVs by using different correction methods in oncological PET/CT imaging.
-To compare between SUV measurements in the tumor and liver using different standardizing parameters such as: body weight, lean body mass and body surface area.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| PET/CT with 18-FDG | Device |
|
| Measure | Description | Time Frame |
|---|---|---|
| -To measure SUVs by using different correction methods in oncological PET/CT imaging. | -To compare between SUV measurements in the tumor and liver using different standardizing parameters such as: body weight, lean body mass and body surface area. | 1/12/2025 to 1/10/2027 |
| Measure | Description | Time Frame |
|---|---|---|
| To determine if SUVbsa is more accurate than SUVbw in obese patients. | -To determine if ''normalization of FDG uptake for the body surface area'' (SUVbsa) is independent of the patient's body size and is more reliable than SUVbw. | 1/12/2025 to 1/10/2027 |
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Inclusion Criteria:
Exclusion Criteria:
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- Cancer patients (> 18 years old) referred to nuclear medicine unit to do F18-FDG PET/CT study.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| HebatAllah Ahmed AbdelRaoof Askar, Assistant Professor, doctor | Contact | +2001003040898 | hebaaskar@aun.edu.eg | |
| Aya Kamel Hamed Ahmed, Resident doctor | Contact | +2001097763423 | aya.17289799@med.aun.edu.eg |
| Name | Affiliation | Role |
|---|---|---|
| Hanan Gamal Eldin Mostafa, Professor, doctor | Assiut University | Study Chair |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 8271040 | Result | Kim CK, Gupta NC, Chandramouli B, Alavi A. Standardized uptake values of FDG: body surface area correction is preferable to body weight correction. J Nucl Med. 1994 Jan;35(1):164-7. | |
| 40589668 | Result | Nakaichi T, Funamoto K, Yamashita S, Yamamoto H, Yokoyama K. Clinical Usefulness of Standardized Uptake Value Normalized to Lean Body Mass Measured Using a Body Composition Analyzer. Cureus. 2025 May 30;17(5):e85089. doi: 10.7759/cureus.85089. eCollection 2025 May. |
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| ID | Term |
|---|---|
| D000072078 | Positron Emission Tomography Computed Tomography |
| ID | Term |
|---|---|
| D049268 | Positron-Emission Tomography |
| D014055 | Tomography, Emission-Computed |
| D007090 | Image Interpretation, Computer-Assisted |
| D003952 | Diagnostic Imaging |
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| Result | Azmi NHM, Suppiah S, Liong CW, Noor NM, Said SM, Hanafi MH, et al. Reliability of standarized uptake value normalized to lean body mass using the liver as a reference organ, in contrast-enhanced 18F-FDG PET/CT imaging. Radiography. 2018;24(2):112-117. doi:10.1016/j.radi.2017.09.006. |
| Result | Ahmed A, Ali M, Salah H, Eisa RE, Mohieldin H, Omer H, et al. Evaluation of uptake values of FDG: Body surface area Vs. body weight correction. Radiat Phys Chem. 2022;201:110482. doi:10.1016/j.radphyschem.2022.110482 . |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D014057 | Tomography, X-Ray Computed |
| D064847 | Multimodal Imaging |
| D011856 | Radiographic Image Enhancement |
| D007089 | Image Enhancement |
| D010781 | Photography |
| D011859 | Radiography |
| D014056 | Tomography, X-Ray |
| D011877 | Radionuclide Imaging |
| D014054 | Tomography |
| D003947 | Diagnostic Techniques, Radioisotope |