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| ID | Type | Description | Link |
|---|---|---|---|
| 2024-344 | Other Identifier | Institutional Review Board of the Plastic Surgery Hospital, Chinese Academy of Medical Sciences |
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| Name | Class |
|---|---|
| The Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College | OTHER |
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Hemifacial atrophy causes one side of the face to become smaller, leading to facial asymmetry. Surgeons often restore facial volume using either autologous fat grafting or free-flap reconstruction. However, it is not fully clear how much facial symmetry improves after surgery when measured objectively using two-dimensional (2D) photographs and three-dimensional (3D) surface scans.
This is a single-center, retrospective observational study of patients with hemifacial atrophy treated between January 2020 and December 2023 at [Plastic Surgery Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College]. We will quantify facial symmetry before surgery and at the first follow-up visit occurring at or beyond 6 months after the initial surgery. Symmetry outcomes will be assessed using standardized 2D photographs for all included patients, and 3D surface scans for a subset of patients. Complications will also be assessed at the first ≥6-month follow-up visit. We will compare changes in symmetry between patients treated with fat grafting and those treated with free-flap reconstruction.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Fat Grafting | Patients with hemifacial atrophy who underwent autologous fat grafting as the initial soft-tissue augmentation procedure. Outcomes were assessed preoperatively and at the first follow-up visit occurring ≥6 months postoperatively. | ||
| Free Flap Reconstruction (ALT) | Patients with hemifacial atrophy who underwent anterolateral thigh (ALT) free-flap reconstruction as the initial soft-tissue augmentation procedure. Outcomes were assessed preoperatively and at the first follow-up visit occurring ≥6 months postoperatively. |
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| Measure | Description | Time Frame |
|---|---|---|
| Change in 2D Facial Symmetry Ratio | Facial symmetry ratio calculated from standardized frontal 2D photographs using computerized photogrammetric analysis. The primary endpoint is the change from preoperative baseline to the first postoperative follow-up visit occurring at or beyond 6 months after the initial surgery. | Baseline (preoperative) and first follow-up visit 6 months postoperatively |
| Measure | Description | Time Frame |
|---|---|---|
| Change in 3D Volumetric Discrepancy Between Hemifaces | Three-dimensional (3D) volumetric discrepancy between the affected and unaffected hemiface measured from 3D surface scans in the subset of participants with available 3D data. Change from baseline to the first ≥6-month follow-up visit. | Baseline (preoperative) and first follow-up visit 6 months postoperatively |
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Inclusion Criteria:
Diagnosis of hemifacial atrophy (Parry-Romberg syndrome).
Underwent initial soft-tissue augmentation with either autologous fat grafting or free-flap reconstruction at the study center between January 2020 and December 2023.
Availability of standardized preoperative assessment and postoperative assessment at the first follow-up visit occurring ≥6 months after surgery (2D photographs required).
Exclusion Criteria:
Follow-up <6 months after the initial surgery.
Missing key imaging/photographic data required for outcome assessment.
Any additional facial augmentation or revision procedure performed before the first ≥6-month follow-up visit.
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Patients with hemifacial atrophy treated at a single center between January 2020 and December 2023 who underwent initial facial volume restoration using autologous fat grafting or free-flap reconstruction. Outcomes were assessed preoperatively and at the first follow-up visit ≥6 months postoperatively. Three-dimensional surface scan analysis was performed in a subset with available 3D data.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Plastic Surgery Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College | Beijing | Beijing Municipality | 100144 | China |
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| ID | Term |
|---|---|
| D005150 | Facial Hemiatrophy |
| ID | Term |
|---|---|
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
| D005155 | Facial Nerve Diseases |
| D003389 | Cranial Nerve Diseases |
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| D009422 |
| Nervous System Diseases |