A Study to Evaluate the Effect of Fasting Duration and Tirzepatide Withholding on the Amount of Food and Fluid in the Stomach in Participants With Type 2 Diabetes Mellitus and Participants With Overweight or Obesity Without Type 2 Diabetes Mellitus

A Study to Evaluate the Effect of Fasting Duration and Temporary Withholding of Tirzepatide on Retained Gastric Contents Using Gastric Ultrasound in Participants With Type 2 Diabetes Mellitus and Participants With Overweight or Obesity Without Type 2 Diabetes Mellitus

The purpose of this study is to evaluate how fasting and stopping the use of tirzepatide affects the amount of food and drink that stays in the stomach after a meal. Ultrasound will be used to check the stomach content after a test meal.

Inclusion Criteria:

• Meet one of the following criteria:

  • Have type 2 diabetes
  • Have obesity
  • Have overweight with at least one health issue related to weight but without type 2 diabetes

Exclusion Criteria:

• Have a condition that affects how their stomach empties
• Have had weight loss surgery
• Have type 1 diabetes
• Have any major medical conditions or histories that could interfere with the study