Cardiovascular Risk Factors in Middle Eastern Patients Wi... | NCT07298668

Studies
Cardiovascular Risk Factors in Middle Eastern Patients With Stroke

NCT07298668

Sponsor

Jordan Collaborating Cardiology Group

Status

Not yet recruiting

Last Update Posted

Dec 23, 2025Actual

Enrollment

2,000Estimated

Phase

Not provided

Conditions

Stroke
Low-Density-Lipoprotein-cholesterol Level
Risk Factors

Interventions

Not provided

Countries

Jordan

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Dec 2025

Overall Recruitment Status or Expanded Access Status

Not yet recruiting

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Dec 31, 2025Estimated

Primary Completion Date

Dec 31, 2026Estimated

Completion Date

Jan 31, 2027Estimated

First Submitted Date

Nov 26, 2025

First Submission Date that Met QC Criteria

Dec 22, 2025

First Posted Date

Dec 23, 2025Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Dec 22, 2025

Last Update Posted Date

Dec 23, 2025Actual

Oversight Module

Has Data Monitoring Committee (DMC)

Yes

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Description Module

Brief Summary

Stroke is a well-known a leading cause of death and disability in the Middle East. There remain many knowledge gaps in evaluating the prevalence of risk factors among patients with stroke in the Middle East. Unravelling the impact of these risk factors and controlling them can positively lower the incidence of stroke. Disparities in stroke risk factors, may well be related to ethnicity of the Middle Eastern populations , will be compared with those among stroke patients in the western literature.

Detailed Description

These clinically relevant issues have not been studied extensively in the Middle East where most of the studies in atherosclerotic cardiovascular disease have focused on acute coronary syndrome more than stroke. Exploring new information on risk factors of stroke in this region that helps fill some of the knowledge gaps.

Stroke has been attributed, in the majority of cases, to the traditional four standard modifiable risk factors of hypertension, type 2 diabetes, dyslipidemia, and cigarette smoking. However, ethnicity and geography account for the interregional differences of the prevalence of risk factors in patients with stroke.

The Jo-SMMART ill evaluate risk factors in 2000 stroke patients in Jordan as a representative of the Middle Eastern population, the prevalence of those with none of the 4 risk factors and the differences in clinical profiles and demographic features on those with risk factors and those with no risk factors. Lipid profile and use of lipid lowering agents will also be evaluated, and furthermore the die0fferneces between young vs old, and men vs women stroke patients ill be addressed.

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

No data available

No data is available for this block.

Enrollment

2,000Estimated

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Prevalence of hypertension in stroke patients (survey interview)	BP more 140/90 or known diagnosis of high blood pressure or patient already on blood pressure medication	Baseline
Prevalence of type 2 diabetes in stroke patients (survey interview)	HbA1c more than 6.5%, or known diagnosis of type 2 diabetes or patient already on anti diabetes medications	BASELINE
Prevalence of elevated serum level of low density lipoprotein cholesterol in stroke patients (survey interview)	Elevated serum level of low density lipoprotein cholesterol > 55 mg/dl or patient already on lipid lowering medication	BASELINE
Prevalence of current cigarette smoking in stroke patients (survey interview)	Known current cigarette smoking of any number of cigarettes per day	BASELINE
Use of lipid lowering therapy (survey interview)	Current use of statin, ezitimibe, PCS9 inhibitor of small interfering RNA agent to lower the LDL-C	BASELINE

Secondary Outcomes

Not provided

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

Diagnosis of stroke upon admission to the hospital
Adult aged 18 years or older
Available lipid profile on hospital admission

Exclusion Criteria:

Stroke diagnosis unconfirmed
age younger than 18 years
No available lipid profile on admission

Accepts Healthy Volunteers

Not provided

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

18 Years

Maximum Age

Not provided

Standard Ages

AdultOlder Adult

Study Population

Will enroll adults admitted to the hospital with a working diagnosis of stroke and then the diagnosis is confirmed by a neurologist. Patients ii be interviewed for data collection of 4 risk factors as above in addition to the serum level of LDLC and the use of lipid lowering agents.

Sampling Method

Non-Probability Sample

Contacts/Locations Module

Central Contacts

Name	Role	Phone	Extension	Email
Laith Habahbeh, MD	Contact	065001000		a.hammoudeh@istisharihospital.com
Ayman Hammoudeh, MD, FACC	Contact	065001000		hammoudeh_ayman@yahoo.com

Overall Officials

Not provided

Locations

Facility	Status	City	State	ZIP	Country	Contacts
Istishari Hospital		Amman		11184	Jordan

IPD Sharing Statement Module

Plan to Share IPD

Yes

Description

All individual participant data will be available in the form of excel sheet with no disclosure of patients names. Can be requested from the study director

Types

Not provided

Time Frame

Not provided

Access Criteria

Not provided

URL

Not provided

Condition Browse Module

MeSH Terms

ID	Term
D020521	Stroke

Ancestor Terms

ID	Term
D002561	Cerebrovascular Disorders
D001927	Brain Diseases
D002493	Central Nervous System Diseases
D009422	Nervous System Diseases

Browse Leaves

Not provided

Browse Branches

Not provided