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This randomized controlled clinical trial aims to evaluate the efficacy of the Er:YAG laser in the removal of impacted mandibular third molars compared to the conventional surgical technique. The study assesses surgical efficiency, postoperative pain, swelling, trismus, and overall patient recovery. The goal is to determine whether the Er:YAG laser provides a safer and less traumatic alternative to traditional bone-cutting methods during third molar surgery.
Impacted mandibular third molars are among the most commonly extracted teeth, and conventional surgical removal often involves bone cutting using rotary instruments, which may increase postoperative morbidity. Laser-assisted surgery, particularly using the Er:YAG laser, has been proposed as a minimally invasive alternative with potential benefits such as reduced thermal damage, improved healing, and less postoperative discomfort.
This study compares Er:YAG laser-assisted bone removal with the conventional bur technique in terms of operative time, intraoperative ease, and postoperative outcomes including pain, edema, and trismus. Patients meeting the eligibility criteria are randomly allocated into two groups: a laser-assisted surgery group and a conventional surgery group. Standardized measurements and follow-up assessments are conducted to evaluate clinical outcomes and determine the effectiveness and safety of the Er:YAG laser in third molar surgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Er:YAG Laser Group | Experimental | Participants in this group will undergo impacted mandibular third molar surgery using the Er:YAG laser for bone removal. |
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| Conventional Rotary Instrument Group | Active Comparator | Participants in this group will undergo impacted mandibular third molar surgery using conventional rotary instruments (bur and handpiece) for bone cutting. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Er:YAG laser | Device | Er:YAG laser (2940 nm) used for bone cutting during impacted mandibular third molar surgery. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Postoperative Pain Score | Postoperative pain will be assessed using a Visual Analog Scale (VAS) ranging from 0 (no pain) to 10 (worst pain) at postoperative intervals. | Immediate postoperative, 24 hours, 3 days, and 7 days |
| Measure | Description | Time Frame |
|---|---|---|
| Postoperative Swelling | Facial swelling will be measured using linear facial measurements (tragus-pogonion and gonion-pogonion distances) preoperatively and at postoperative intervals. | Immediate postoperative, 24 hours, 3 days, and 7 days |
| Postoperative Trismus |
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Inclusion Criteria:
• Adults aged 20-30 years requiring surgical extraction of a mesioangular impacted mandibular third molar.
Exclusion Criteria:
• Systemic medical conditions affecting bone healing or postoperative response (e.g., uncontrolled diabetes, immunodeficiency, metabolic bone disorders).
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| Name | Affiliation | Role |
|---|---|---|
| Karim Elhaw, MSc (Oral Laser Applications) | Alexandria University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Dentistry, Alexandria University | Alexandria | Alexandria Governorate | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 42243813 | Derived | Elhaw KA, Abdelhakim AA, Dominguez J A, Eldibany RM, Tost A E. Efficacy of Er:YAG laser in removal of impacted mandibular third molars (a randomized controlled clinical trial). BMC Oral Health. 2026 Jun 5;26(1):1060. doi: 10.1186/s12903-026-08790-w. |
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The plan for sharing individual participant data (IPD) has not yet been determined. Decisions regarding IPD sharing will depend on institutional policies, ethical approvals, and future publication requirements.
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| ID | Term |
|---|---|
| D053844 | Lasers, Solid-State |
| ID | Term |
|---|---|
| D007834 | Lasers |
| D055096 | Optical Devices |
| D004864 | Equipment and Supplies |
| D055618 | Radiation Equipment and Supplies |
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Participants are randomly assigned into two parallel groups: Er:YAG laser-assisted surgery and conventional rotary instrument surgery.
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No masking was performed because both the surgeon and the participants were aware of the intervention type.
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| Conventional Rotary Instruments Surgery | Procedure | Conventional rotary instruments used for bone removal during surgical extraction of impacted mandibular third molars. |
|
Maximum interincisal mouth opening will be measured in millimeters preoperatively and at postoperative intervals to assess trismus. |
| Immediate postoperative, 24 hours, 3 days, and 7 days |
| Bone Density | Bone density at the extraction site will be assessed using standardized digital radiographs. Gray-scale values will be measured at predetermined reference points to compare bone healing between groups. | Immediate postoperative, 1 month, and 3 months |