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Determination of fibrin clot properties along with thrombin generation in women after urigynecological surgery.
Fibrin clot permeability and susceptibility to lysis along with thrombin generation
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Women with urine incontinence/ uterine prolapse | Healthy women with urine incontinence/ uterine prolapse qualified for urogynecological surgery |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| determination of fibrin clot properties | Diagnostic Test | Determination of fibre clot properties and thrombin generation in women with uterine prolapse/ urine incontinence before and after urogynecological surgery. |
| Measure | Description | Time Frame |
|---|---|---|
| fibrin clot phenotype | fibrin clot permeability and susceptibility to lysis | December 2025 till May 2026 |
| Thrombin generation | Endogenous thrombin generation | December 2025 till May 2026 |
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Inclusion Criteria:
Exclusion Criteria:
Participants with urine incontinence and uterine prolapse will be enrolled.
Women with diagnosed uterine prolapse or urine incontinence after failure of pharmacotherapy.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Magdalena MP Piróg, MD, PhD | Contact | +48 604514915 | magda.m.pulka@gmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Gynecological Endocrinology Department | Recruiting | Krakow | Małopolska | 31-501 | Poland |
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| ID | Term |
|---|---|
| D014596 | Uterine Prolapse |
| D053206 | Nocturnal Enuresis |
| ID | Term |
|---|---|
| D014591 | Uterine Diseases |
| D005831 | Genital Diseases, Female |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
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| D000091642 | Urogenital Diseases |
| D000091662 | Genital Diseases |
| D056887 | Pelvic Organ Prolapse |
| D011391 | Prolapse |
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D004775 | Enuresis |
| D014555 | Urination Disorders |
| D014570 | Urologic Diseases |
| D052801 | Male Urogenital Diseases |
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
| D019960 | Elimination Disorders |
| D001523 | Mental Disorders |