Impact of Endo-vac Therapy for Esophago-jejunal Anastomotic Leak

Prospective Observational Study on Endo-vac Therapy for Esophago-jejunal Anastomotic Leak

The goal of this observational study is to assess the impact of endoscopic vacuum therapy in patients who underwent total gastrectomy due to gastric cancer and developed esophago-jejunal anastomotic leakage. The main outcomes to be investigated are the following:

Primary endpoint: mortality rate Secondary endpoints: morbidity rate, time from AL diagnosis to discharge, patients satisfactory rate.

Patients who are diagnosed with asophago-jejunal anastomotic leakage will undergo endoscopic vacuum therapy. Local source control may be additionally achieved with para-anastomotic drains.

Inclusion Criteria:

• patients who developed esophago-jejunal anastomotic leak less than 50% of circumference of anastomosis
• patients who developed esophago-jejunal anastomotic leak and remained stable at the moment of diagnosis with no indications for diversion surgery

Exclusion Criteria:

• unstable patients who developed esophago-jejunal anastomotic leak
• patients who developed esophago-jejunal anastomotic leak more than 50% or anastomotic circumference
• patients who rejected endoscopic vacuum therapy