Group 2 (high-intensity laser therapy (HILT)) will undergo pulsed laser therapy using the HIRO 3 device (ASA Laser, Arcugnano, Italy) five times a week for 6 weeks (a total of 30 sessions, one session per day) in addition to the physical therapy program. During each session, a three-phase treatment program will be administered to patients once a day, accompanied by a physical therapist, consisting of nerve/tendon gliding exercises.

The sham-HILT group will receive sham laser therapy using the HIRO 3 device (ASA Laser, Arcugnano, Italy) five times a week for six weeks (a total of 30 sessions, one session per day) in addition to the physical therapy program. After patients see that the device is turned on during the sham application, the same treatment will be applied to the same treatment area for the same duration without allowing laser current output from the device.

The Self-Rating of Neuropathic Symptoms and Signs (S-LANSS) scale will be administered to all patients to determine the presence of neuropathic pain. The SLANSS scale is a measure used to distinguish neuropathic pain from nociceptive pain. Unlike the LANSS scale, the physician does not examine the patient in this scale, making it easier to administer. The S-LANSS scale consists of a total of 7 questions. The patient fills out this scale themselves. The first 5 questions consist of questions that inquire about pain symptoms, while the last 2 questions include a clinical examination that the patient performs on themselves. The answers to the questions are yes/no. Each question has a different score. The total score on the scale is 24. A total score of 12 or higher suggests neuropathic pain. The Turkish version of the S-LANSS scale has been validated and is reliable.

This scale, used to assess sleep quality, consists of 24 questions that inquire about sleep quality over the past 4 weeks. The scale has 7 components, each of which is scored on a scale of 0-3. The total PUKİ score ranges from 0 to 21, with a score higher than 5 indicating poor sleep quality. Turkish validity and reliability studies have been conducted.

Created to assess functional status and symptoms by focusing on physical function in the upper extremities. This questionnaire contains a total of 11 items. Symptoms or difficulty are rated on a scale of 1 to 5. At least 10 questions must be answered to calculate the Quick DASH score. The calculation result is rated between 0 and 100.0. 0 indicates no difficulty or symptoms, while 100 indicates no activity or severe symptom

The compound muscle action potential amplitude (CMAP) will be obtained via surface electrodes placed on the abductor pollicis brevis muscle. The active recording electrode will be placed on the muscle belly and the reference electrode on the tendon insertion. The median nerve will be stimulated 8 cm proximal to the active recording electrode. Distal motor latencies will be measured from the onset of the stimulus artifact to the onset of the CMAP.

CMAPs will be obtained via surface electrodes placed on the abductor pollicis brevis muscle. The active recording electrode will be placed on the muscle belly, and the reference electrode will be placed at the tendon insertion. The median nerve will be stimulated 8 cm proximal to the active recording electrode. The amplitude of the CMAP will be measured from the baseline to the negative peak.

The compound muscle action potential amplitude (CMAP) will be obtained via surface electrodes placed on the abductor pollicis brevis muscle. The median nerves will be stimulated at the wrist and antecubital fossa levels. Distal motor latencies will be measured from the onset of the stimulus artifact to the onset of the CMAP. Motor nerve conduction velocity will be calculated by dividing the distance by the distal motor latency.

Sensory nerve action potential amplitudes (SNAP) will be obtained using the orthodromic method and recorded with the second ring electrodes. The median nerves will be stimulated at the proximal and distal interphalangeal joints of the index finger and palm. Distal sensory latencies will be measured from the onset of the stimulus artifact to the onset of the SNAP.

Sensory nerve action potential amplitudes (SNAP) will be obtained using an orthodromic method and recorded using surface electrodes placed on the wrist. The median nerves will be stimulated at the proximal and distal interphalangeal joints of the index finger. Distal sensory latencies will be measured from the onset of the stimulus artifact to the onset of the SNAP. Sensory nerve conduction velocity will be calculated by dividing the distance by the distal sensory latency.

Sensory nerve action potential amplitudes (SNAP) will be obtained using an orthodromic method and recorded with ring electrodes. The median nerves will be stimulated at the proximal and distal interphalangeal joints of the index finger. Distal sensory latencies will be measured from the onset of the stimulus artifact to the onset of the SNAP. Sensory nerve conduction velocity will be calculated by dividing the distance by the distal sensory latency.

A hand dynamometer (JAMAR) will be used to assess grip strength. The patient will perform three consecutive tests while sitting with shoulders abducted and neutrally rotated, elbow flexed at 90°, and forearm and wrist in a neutral position. The best of these measurements will be recorded in kilograms.

A pinchmeter will be used to evaluate pulp-to-pulp grip strength. The patient will sit with shoulders abducted and neutrally rotated, elbow flexed at 90°, and forearm and wrist in a neutral position, and will perform three consecutive tests. The best of these measurements will be recorded in kilograms.