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| Name | Class |
|---|---|
| The Hershey Company | INDUSTRY |
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The objective of this study is to compare the appearance of amino acids in circulation following consumption of two protein beverages in adults. Secondary objectives of this study are to assess changes in gastrointestinal tolerability, glycemia, markers of subjective and physiological appetite, and nausea.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Experimental - Protein Beverage | Experimental | Protein powder mixed into 8 oz of water |
|
| Active Control - Protein Beverage | Active Comparator | Control protein powder mixed into 8 oz of water |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Protein Powder | Dietary Supplement | Contains 30 g of protein |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Total Amino Acid net incremental area under the curve (niAUC) | Difference between conditions in the niAUC for the total amino acid level in plasma | 5-12 hours post-beverage consumption |
| Measure | Description | Time Frame |
|---|---|---|
| Total Amino Acids area under the curve (AUC) | Differences between conditions in AUC for the total amino acid level in plasma | 0-5 hours, 5-12 hours, 0-12 hours, and 8-12 hours |
| Total Amino Acids niAUC |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ocean Wellness Center | Miami Gardens | Florida | 33169 | United States |
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| Control Protein Powder |
| Dietary Supplement |
Contains 30 g of protein |
|
Difference between conditions in the niAUC for the total amino acid level in plasma
| 0-5 hours, 0-12 hours, and 8-12 hours |
| Maximum concentration for total amino acids | Difference between conditions in the maximum concentration for total amino acids in plasma | 0-12 hours |
| Baseline-adjusted maximum concentration for total amino acids | Difference between conditions in the baseline-adjusted maximum concentration for total amino acids in plasma | 0-12 hours |
| Time to maximum concentration for total amino acids | Differences between conditions in the time to maximum concentration for total amino acid levels in plasma | 0-12 hours |
| Glucagon-like peptide-1 AUC | Differences between conditions in the AUC for glucagon-like peptide-1 | 0-5 hours, 5-12 hours, and 0-12 hours |
| Glucagon-like peptide-1 niAUC | Differences between conditions in the niAUC for glucagon-like peptide-1 | 0-5 hours, 5-12 hours, and 0-12 hours |
| Peptide YY AUC | Differences between conditions in the AUC for peptide YY | 0-5 hours, 5-12 hours, and 0-12 hours |
| Peptide YY niAUC | Differences between conditions in the niAUC for peptide YY | 0-5 hours, 5-12 hours, and 0-12 hours |
| Ghrelin AUC | Differences between conditions in the AUC for ghrelin | 0-5 hours, 5-12 hours, and 0-12 hours |
| Ghrelin niAUC | Differences between conditions in the niAUC for ghrelin | 0-5 hours, 5-12 hours, and 0-12 hours |
| Glucose-dependent insulinotropic polypeptide AUC | Differences between conditions in the AUC for glucose-dependent insulinotropic polypeptide | 0-5 hours, 5-12 hours, and 0-12 hours |
| Glucose-dependent insulinotropic polypeptide niAUC | Differences between conditions in the niAUC for glucose-dependent insulinotropic polypeptide | 0-5 hours, 5-12 hours, and 0-12 hours |
| Markers of subjective appetite AUC | Difference between conditions in the AUC for markers of subjective appetite (hunger, fullness, desire to eat, and prospective consumption) measured by the visual analog scale | 0-5 hours, 5-12 hours, and 0-12 hours |
| Markers of subjective appetite niAUC | Difference between conditions in the niAUC for markers of subjective appetite (hunger, fullness, desire to eat, and prospective consumption) measured by the visual analog scale | 0-5 hours, 5-12 hours, and 0-12 hours |
| Essential Amino Acids AUC | Differences between conditions in AUC for the essential amino acid level in plasma | 5-12 hours and 8-12 hours |
| Essential Amino Acids niAUC | Difference between conditions in the niAUC for the essential amino acid level in plasma | 5-12 hours and 8-12 hours |
| Leucine AUC | Differences between conditions in AUC for the leucine level in plasma | 5-12 hours |
| Leucine niAUC | Difference between conditions in the niAUC for the leucine level in plasma | 5-12 hours |
| Maximum concentration for essential amino acids | Difference between conditions in the maximum concentration for essential amino acids in plasma | 0-12 hours |
| Maximum concentration for leucine | Difference between conditions in the maximum concentration for leucine in plasma | 0-12 hours |
| Total amino acids at t = 12 hours | Difference between conditions in the total amino acid level at t = 12 hours | t = 12 hours |
| Essential Amino Acids at t = 12 hours | Difference between conditions in the essential amino acid level at t = 12 hours | t = 12 hours |
| Baseline-adjusted maximum concentration for essential amino acids | Difference between conditions in the baseline-adjusted maximum concentration for essential amino acids in plasma | 0-12 hours |
| Baseline-adjusted maximum concentration for leucine | Difference between conditions in the baseline-adjusted maximum concentration for leucine in plasma | 0-12 hours |
| Time to maximum concentration for essential amino acids | Differences between conditions in the time to maximum concentration for essential amino acid levels in plasma | 0-12 hours |
| Time to maximum concentration for leucine | Differences between conditions in the time to maximum concentration for leucine levels in plasma | 0-12 hours |