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Background: Older adults have a reduced ability to build and maintain muscle mass due to age-related changes in the muscular system. The resulting sarcopenia can lead to a number of health problems and limitations, such as an increased risk of falling and reduced mobility, which can affect quality of life and increase the risk of disease. To increase muscle mass and strength, high-intensity resistance training with loads of 70 to 85% of the repetition maximum (1RM) is recommended. However, this type of training poses a major challenge in the rehabilitation sector, as there is also an increased risk of injury due to physical limitations in old age. According to current research, low-intensity occlusion training could therefore represent a safe and effective training alternative. The aim of this study is therefore to examine the feasibility and effects of blood flow restriction training (BFR) on general health in older adults in a rehabilitative setting.
The study is a randomized controlled trial with a pre-post design. Participants will be recruited from the of St. Marien Hospital Geriatric Rehabilitation Center in Cologne, Germany. Patients will be randomized into 2 groups. The intervention group will receive BRF training on a stationary cycling ergometer five times a week over a period of two weeks, while the control group will receive sham-BFR training.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention Group | Experimental | Blood-Flow-Restriction Training |
|
| Control Group | Active Comparator | Sham-Blood-Flow-Restriction Training |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Stationary Bike + Blood-Flow-Restriction | Device | Cycling Intensity individualized + 60% LOP |
|
| Measure | Description | Time Frame |
|---|---|---|
| Muscle Strength | Isometric Maximal Strength Test of the Knee Extensors (in kg) | Pre-Rehabilitation to Post-Rehabilitation (after 2 weeks) |
| Timed Up and Go Test | The Timed Up and Go Test (TUG) is a widely used English-language assessment for measuring functional mobility and fall risk in older adults. It records the time required to stand up from a chair, walk three meters, turn around, and sit down again. | Pre-Rehabilitation to Post-Rehabilitation (after 2 Weeks) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Alexander Franz, Dr. med., B.Sc. | Contact | +491703750718 | alexander.franz@ukbonn.de |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| St. Marien-Hospital Köln | Recruiting | Cologne | North Rhine-Westphalia | 50668 | Germany |
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| Stationary Bike + Sham-Blood-Flow-Restriction | Device | Cycling Intensity individualized + 20mmHg |
|