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Women with psoriasis usually develop many complications including polysyctic ovarian syndrome (PCOS). Nowdays, diet restriction combimed with phsyical exercises may improve both problems
Forty Women with psoriasis with PCOS will be enrolled to be catogrized to Group I or group II. Group I will enroll twenty females with PCOS and Psoriasis who will apply forty minutes walking on treadmill three times per week. Also Group I will follow low calorie diet and daily metformin for 12 weeks. Group II will will enroll twenty females with PCOS and Psoriasis who will follow low calorie diet and daily metformin for 12 weeks
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| group number 1 | Experimental | Group I will enroll twenty females with PCOS and Psoriasis who will apply forty minutes walking on treadmill three times per week. Also Group I will follow low calorie diet and daily metformin for 12 weeks. |
|
| group number 2 | Active Comparator | Group II will will enroll twenty females with PCOS and Psoriasis who will follow low calorie diet and daily metformin for 12 weeks |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| exercise and diet restriction | Behavioral | Group I will enroll twenty females with PCOS and Psoriasis who will apply forty minutes walking on treadmill three times per week for 12 weeks. Also Group I will follow low calorie diet and daily metformin for 12 weeks. |
| Measure | Description | Time Frame |
|---|---|---|
| Psoariasis area and severity index | is an index used to express the severity of psoriasis. It combines the severity (erythema, induration and desquamation) and percentage of affected area | it will be measured after 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| body mass index | it will be assessed after emptying bladder and bowel | It will be measured after 12 weeks |
| waist circumference | it will be measured at level of ambilicus |
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Inclusion Criteria:
Exclusion Criteria:
based on self-representation of gender identity.
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ali MA Ismail, lecturer | Contact | 01005154209 | ali.mohamed@pt.cu.edu.eg | |
| Ali mohamed, lecturer | Contact | 01031321109 | allooka2012@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Ali MA Ismail, lecturer | Cairo University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cairo University | Recruiting | Giza | Dokki | Egypt |
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| ID | Term |
|---|---|
| D011565 | Psoriasis |
| D011085 | Polycystic Ovary Syndrome |
| ID | Term |
|---|---|
| D017444 | Skin Diseases, Papulosquamous |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D010048 | Ovarian Cysts |
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| ID | Term |
|---|---|
| D015444 | Exercise |
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
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| diet restriction | Behavioral | Group II will will enroll twenty females with PCOS and Psoriasis who will follow low calorie diet and daily metformin for 12 weeks |
|
| It will be measured after 12 weeks |
| waist hip ratio | it will be assessed after dividing waist circumference on hip circumference | It will be measured after 12 weeks |
| testesterone | it will be assessed in serum | it will be measured after 12 weeks |
| ratio of luteinizing hormone and follicle-stimulating hormone | it is anindicator on function of sex hormones | It will be measured after 12 weeks |
| Dehydroepiandrosterone | it will be assessed in plasma | It will be measured after 12 weeks |
| Dermatology life Quality Index | it assess impact of skin disease on quality of life | It will be measured after 12 weeks |
| insuiln | it will be assessed in plasma | It will be measured after 12 weeks |
| fasting blood glucose | it will be assessed in plasma | It will be measured after 12 weeks |
| HOMA-IR | Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) is classically considered to be a good insulin resistance (IR) index | It will be measured after 12 weeks |
| triglycerides | it will be assessed in plasma | It will be measured after 12 weeks |
| total cholesterol | it will be assessed in plasma | It will be measured after 12 weeks |
| high density lipoprotein | it will be assessed in plasma | It will be measured after 12 weeks |
| low density lipoprotein | it will be assessed in plasma | It will be measured after 12 weeks |
| systolic blood pressure | it will be assessed via manual sphygmmanometer | It will be measured after 12 weeks |
| diatolic blood pressure | it will be assessed via manual sphygmmanometer | It will be measured after 12 weeks |
| D003560 | Cysts |
| D009369 | Neoplasms |
| D010049 | Ovarian Diseases |
| D000291 | Adnexal Diseases |
| D005831 | Genital Diseases, Female |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D000091662 | Genital Diseases |
| D006058 | Gonadal Disorders |
| D004700 | Endocrine System Diseases |