Non-invasive Intracranial Pressure Monitoring in Brain Tumor Patients

Non-invasive Intracranial Pressure Monitoring in Brain Tumor Patients: A Prospective Observational Study of Optic Nerve Sheath Diameter Dynamics

This research protocol focuses on the pre- and post-operative evaluation of ICP using non-invasive methods, particularly in the context of surgery for brain tumor removal. By utilizing ocular ultrasound to measure ONSD and ONSD/ETD ratios, this study hypothesizes that the utility of these parameters in monitoring ICP pre- and post-operative periods could be effective.

This research protocol focuses on the pre- and post-operative evaluation of ICP using non-invasive methods, particularly in the context of brain tumor resection surgery. By utilizing ocular ultrasound to measure ONSD and ONSD/ETD ratios, this study hypothesizes that the utility of these parameters in monitoring ICP pre- and post-operative periods could be effective.

This study aims to evaluate the effectiveness of the ONSD and the ONSD/ETD ratio using ultrasound as a non-invasive method for measuring intracranial pressure pre- and post-operatively in brain tumor patients.

Inclusion Criteria:

• • Adult patients (>21 years) undergoing brain tumor resection surgery.

  • Preoperative imaging-confirmed diagnosis of the tumor.
  • American Society of Anesthesiologists (ASA) physical status II to IV
  • Consent to participate in the study.

Exclusion Criteria:

• • Preexisting ocular conditions affecting the optic nerve or globe integrity, such as glaucoma, thyroid-associated ophthalmopathy, or other optic nerve diseases.

  • Combined ocular and optic nerve injuries at admission.
  • History of cranial trauma, prior neurosurgery, or lumbar puncture performed within 2 weeks before the measurement of optic nerve sheath diameter (ONSD).
  • History of subarachnoid hemorrhage (SAH).
  • Serious complications that could affect life expectancy, such as hematological disorders or malignancies.
  • Refusal to participate or withdrawal of consent at any stage.