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To evaluate the long-term safety of RGL-193 capsid injection in patients with primary Parkinson's disease over 5 years
An open-label, observational, long-term follow-up study evaluating the safety and efficacy of RGL-193 capsid injection in patients with primary Parkinson's disease over 5 years
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Subjects who have previously participated in RGL-193-related studies and have received RGL-193 treat |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Observational | Other | Long-term observational |
|
| Measure | Description | Time Frame |
|---|---|---|
| To evaluate the long-term safety of RGL-193 capsid injection in patients with primary Parkinson's disease over 5 years | 52 weeks after core-shell injection |
| Measure | Description | Time Frame |
|---|---|---|
| Assess the metabolic activity of related enzymes in patients with primary PD over 5 years following RGL-193 capsid injection. | 52 weeks after core-shell injection |
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Inclusion Criteria:
Exclusion Criteria:
None
-
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Patients with mid-to-late stage Parkinson's disease
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Chaoshi Niu | Contact | +86 13855186208 | niuchaoshi@163.com | |
| Chi Xiong | Contact | +86 18709857411 | xiongchi@ustc.edu.cn |
| Name | Affiliation | Role |
|---|---|---|
| Chaoshi Niu | The First Affiliated Hospital of University of Science and Technology of China | Principal Investigator |
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Serum, Vector
| ID | Term |
|---|---|
| D010300 | Parkinson Disease |
| ID | Term |
|---|---|
| D020734 | Parkinsonian Disorders |
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D009069 | Movement Disorders |
| D000080874 | Synucleinopathies |
| D019636 | Neurodegenerative Diseases |
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| ID | Term |
|---|---|
| D057832 | Watchful Waiting |
| ID | Term |
|---|---|
| D017063 | Outcome Assessment, Health Care |
| D010043 | Outcome and Process Assessment, Health Care |
| D011787 | Quality of Health Care |
| D006298 | Health Services Administration |
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