The aim of the study presented here is to assess the effects of exoskeleton training on performance in a real hypergravity situation. In particular, it will analyze fine motor control, autonomic nervous system regulation and metabolic responses. To this end, the study will compare two groups during a pointing exercise in a centrifuge (hypergravity). One group will have been trained to do this exercise using an exoskeleton, while the other will have been familiarized with the task without the exoskeleton. It will assess whether the exoskeleton can be an effective and accessible training tool for astronauts.

Inclusion Criteria:

• Maximum weight of 90 kg
• Maximum sitting butt-to-shoulder distance of 70 cm
• Certified as healthy by a comprehensive clinical assessment
• Normal or corrected to normal vision
• Right-handed tested with Edinburgh-Handedness-Inventory-Test (≥6th percentile, on https://www.brainmapping.org/shared/Edinburgh.php)
• Non smokers
• No alcohol or drug dependence, no medical treatment on a regular basis
• Affiliated to a Social Security system and, for non-French resident, holding a European Health Insurance Card (EHIC) or a Global Health Insurance Card (GHIC).
• Free of any engagement during the study
• Test subjects must be able to understand and speak English
• Who agreed to take part in the study and signed the informed consent

Exclusion Criteria:

• Left-handed tested with Edinburgh-Handedness-Inventory-Test (<6th percentile)
• Subjects with experience in experiments on a short arm human centrifuge or under real hyper-gravity
• Non-tolerance to the centrifugation
• Any history or presence of clinically relevant chronic disease
• Refusal to give permission to contact his general practitioner,
• Subject who, in the judgment of the investigator, is likely to be non-compliant during the study, or unable to cooperate because of a language problem or poor mental development,
• Subject in the exclusion period of a clinical research,
• Subject who has received more than 6000 Euros within 12 months for being a research subject,
• Subject who cannot be contacted in case of emergency,
• Vulnerable people according to law "Code de la Santé Publique" (L1121-5 to L1121-8)