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Understanding, through accurate and reliable volumetric analysis, how the biomaterial (LPRF) and the thickness of the vestibular bone plate influence changes in bone volume after extraction, is essential for making clinical decisions that impact implant-supported rehabilitation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| platelet rich firbrin |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Alveolar socket preservation with graft and flap surgery | Procedure | teeth to either the control group (coagulant-filled alveoli) or the test group (alveoli filled with platelet-rich fibrin and LPRF leukocytes) |
| Measure | Description | Time Frame |
|---|---|---|
| bone volume after 16 weeks | 16 weeks | |
| aveolar bone contraction | 4 months |
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This prospective clinical study was conducted in accordance with the ethical principles outlined in the Declaration of Helsinki and received approval from the Research Ethics Committee of Guarulhos University, São Paulo, Brazil (CEP-UnG #. 515.153). Thirty-nine patients (24 women and 15 men), aged between 22 and 80 years, who were in overall good health, non-diabetic, periodontally healthy, non-smokers, free of blood dyscrasias, not pregnant or lactating, and requiring extraction of non-contiguous, compromised teeth due to root fractures, caries, unsuccessful endodontic treatment, root resorption, or orthodontic reasons, were enrolled.
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Subjects with indication of tooth extraction
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| ID | Term |
|---|---|
| D003731 | Dental Caries |
| D016388 | Tooth Loss |
| ID | Term |
|---|---|
| D017001 | Tooth Demineralization |
| D014076 | Tooth Diseases |
| D009057 | Stomatognathic Diseases |
| D010510 | Periodontal Diseases |
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| ID | Term |
|---|---|
| D014180 | Transplantation |
| ID | Term |
|---|---|
| D013514 | Surgical Procedures, Operative |
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| D009059 |
| Mouth Diseases |