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The objective of this observational study is to systematically compare the efficacy and patient prognosis between auxiliary liver transplantation and living donor liver transplantation, and to explore the postoperative recovery, survival rate, rejection, postoperative complications, and long-term prognosis of patients undergoing auxiliary liver transplantation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| auxiliary liver transplantation | Patients who underwent auxiliary liver transplantation at our center during the study period | ||
| living donor liver transplantation | Patients who underwent traditional orthotopic living donor liver transplantation at our center during the study period. |
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| Measure | Description | Time Frame |
|---|---|---|
| Overall survival | Within one year after liver transplantation |
| Measure | Description | Time Frame |
|---|---|---|
| Complications | Rejection, vascular, biliary and other related complications | Within one year after liver transplantation |
| changes in peripheral blood lymphocytes | Peripheral blood lymphocytes during the early post-transplant period were compared between the auxiliary and living donor liver transplantation groups to identify differences. |
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Inclusion Criteria:
Exclusion Criteria:
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Patients who were treated at the Liver Transplantation Center of Beijing Friendship Hospital, Capital Medical University between December 2025 and December 2028, and who underwent either auxiliary liver transplantation (study group) or conventional liver transplantation (control group).
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Bin Li | Contact | +8619935943688 | libin_2024@163.com |
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Blood samples were collected at 3 days, 7 days, 14 days, 1 month, and 3 months postoperatively for Olink proteomics analysis. Peripheral blood mononuclear cells (PBMCs) were isolated for flow cytometry detection.
| within 3 months after liver transplantation |