This study compares the efficacy of two drugs i.e Adrenaline and dopamine in fluid refractory type of septic shock which is a dreadful medical condition especially in children. The efficacy will be checked based on heart rate , GCS, capillary refill time , palpable pripheral pulse , urine output and systolic blood pressure.

This is a randomized control trial in which children / patients diagnosed with Fluid refractory Septic shock will be provided with one of the two drugs ina randomzied way and their efficacy will be assesed on the basis of correction of various parameters at various points of time.

Inclusion Criteria:

Patients of both Genders having age range between 1month and 12 years with diagnosis of fluid refractory septic shock as per operational definition.

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Exclusion Criteria:

• Patients with

  1. cardiopumonary Bypass during last 5 days
  2. Chronic Systemic disease like Chronic kidney Disease , cerebral palsy, congenital heart disease
  3. neuromuscular discorder
  4. Metabolic disorders
  5. Those who already had treatment at periphery for hypovolemia without any record of medication or sequential organ failure at presentation