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Our goal in this work is to compare the predictive accuracy of the REDS score versus qSOFA in identifying in-hospital mortality among ED patients with suspected sepsis and improving outcomes in ED patients.
Sepsis is a life threatening condition and a major cause of morbidity and mortality in emergency department worldwide.Patients at high-risk of death may be identified by using an evidence based risk-stratification score. The ED is a busy and hard environment and any score that is used should be easy to calculate using readily available variables. The objective criteria defining sepsis, a minimum two-point increase as in qSoFA score .
The REDS (Risk-stratification of Emergency Department suspected Sepsis) score is a tool used to assess the risk of mortality in patients with suspected sepsis in the emergency department. It combines several factors including age, altered mental state, respiratory rate, systolic blood pressure, serum albumin, INR, lactate levels, and refractory hypotension. A score of 3 or more is considered high-risk. Our goal in this work is to compare the predictive accuracy of the REDS score versus qSOFA in identifying in-hospital mortality among ED patients with suspected sepsis and improving outcomes in ED patients.
The REDS score includes the following variables, each assigned a point value:
Age: ≥ 65 years old (1 point) Altered Mental State: (1 point) Respiratory Rate: ≥ 22 breaths/min (1 point) Systolic Blood Pressure: ≤ 100 mm Hg (1 point) Serum Albumin: ≤ 27 g/L (1 point) INR: ≥ 1.3 (1 point) Lactate: 2.1-3.9 mmol/L (1 point), ≥ 4 mmol/L (3 points) Refractory Hypotension: (2 points for lactate ≤ 2 mmol/L, 3 points for lactate >2 mmol/L)
Interpreting the REDS score:
0-2: Low risk of death 3 or more: High risk of death The REDS score is a useful tool for emergency departments to quickly identify patients who may be at higher risk of mortality from sepsis and need more aggressive or immediate treatment.The quick SOFA (qSOFA) score is a bedside tool used to quickly assess the risk of death or prolonged intensive care unit stay in patients with suspected infection. It uses three criteria: respiratory rate, altered mental status, and systolic blood pressure. A score of 2 or more indicates a higher risk.
qSOFA Criteria:
Scoring:
Each criterion met scores 1 point. A score of 2 or more indicates a higher risk of poor outcome. qSOFA helps identify patients with suspected infection who are likely to have sepsis. It is a rapid assessment tool that can be used in urgent and resource-limited settings
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients will be randomly assigned to two groups: 1) Group A 2)Group B | Patients will be randomly assigned to two groups:
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Sphygmomanometer | Device | Mercury sphygmomanometer for measuring blood pressure |
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| Measure | Description | Time Frame |
|---|---|---|
| Primary outcome | primary outcome will be mortality during the 30 day follow-up | 30 day |
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Inclusion Criteria:
Exclusion Criteria:
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Our goal in this work is to compare the predictive accuracy of the REDS score versus qSOFA in identifying in-hospital mortality among ED patients with suspected sepsis and improving outcomes in ED patients.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Mostafa Nageh mohamed, M.B.B. Ch | Contact | +01119618014 | mostafanageh999@gmail.com | |
| Bassant said Mousa Associate Prof of Emergency department Faculty of medicine, Study Principal Investigator | Contact | 01227062927 |
| Name | Affiliation | Role |
|---|---|---|
| Mohamed Anwar, Consultant of Anathesia ICU | Assiut University | Principal Investigator |
| Haitham Mohammed Ahmed, Lecturer of Anesthesia,ICU | Assiut University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Assiut | Asyut | Abo Tig | 71641 | Egypt |
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| ID | Term |
|---|---|
| D019722 | Sphygmomanometers |
| ID | Term |
|---|---|
| D019719 | Diagnostic Equipment |
| D004864 | Equipment and Supplies |
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