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| Name | Class |
|---|---|
| L'Oreal | INDUSTRY |
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Skin moisturization is important for patients with atopic dermatitis, commonly known as eczema. Moisturizing right after bathing is widely accepted as the best method to keep skin hydrated. However, there is conflicting research on the timing of moisturizing. The goal of this clinical study is to evaluate the preference of moisturizing while showering/bathing compared to after towel drying in adolescents aged 12-18 with eczema. The main question it aims to answer are:
Researchers will compare applying moisturizer while in the shower/bath to after towel drying and to which technique is preferred among participants and if there are different effects on eczema and skin hydration.
Participants will:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Moisturizing while in shower/bath | Experimental |
| |
| Moisturizing after towel drying | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Moisturizing while in shower/bath | Behavioral | Applying moisturizer in the shower/bath. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Proportion of Participants Preferring Each Moisturization Technique | Participant reported preference of moisturization technique | Through study completion, an average of 2 months. |
| Measure | Description | Time Frame |
|---|---|---|
| Skin Hydration Level | Skin electrical capacitance measured using Corneometer® CM825 as an indicator of skin hydration. | Through study completion, an average of 2 months. |
| Measure | Description | Time Frame |
|---|---|---|
| Eczema Severity Score | Eczema severity will be assessed by clinicians using the Validated Investigator Global Assessment Scale for Atopic Dermatitis (vIGA-ADâ„¢). Scores range from 1 to 4, with higher scores indicating more severe eczema/atopic dermatitis (worse outcome). | Through study completion, an average of 2 months. |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Wingfield Rehmus, MD, MPH | Contact | 1-604-875-2606 | dermatologyresearch@cw.bc.ca |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| BC Children's Hospital | Vancouver | British Columbia | Canada |
Individual participant data will not be shared, but aggregated data from all participants will be shared.
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| ID | Term |
|---|---|
| D003876 | Dermatitis, Atopic |
| D004485 | Eczema |
| ID | Term |
|---|---|
| D012873 | Skin Diseases, Genetic |
| D030342 | Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D003872 | Dermatitis |
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| Moisturizing after towel drying | Behavioral | Applying moisturizer out of the shower/bath after towel drying. |
|
| Itch Intensity |
Itch intensity will be assessed using a patient-reported Numeric Rating Scale (NRS) ranging from 1 to 10, where higher scores indicate greater itch severity (worse outcome). Participants will report both average itch and worst itch experienced within the past 24 hours. |
| Through study completion, an average of 2 months. |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D017443 | Skin Diseases, Eczematous |
| D006969 | Hypersensitivity, Immediate |
| D006967 | Hypersensitivity |
| D007154 | Immune System Diseases |