Pulsed Radiofrequency Versus Hyaluronidase Hydrodissection for Treatment of Carpal Tunnel Syndrome

Comparison of Ultrasound Guided Pulsed Radiofrequency Versus Hyaluronidase Hydrodissection for Treatment of Carpal Tunnel Syndrome, a Prospective, Randomized, Controlled Clinical Study

The aim of this study is to compare the clinical efficacy and safety of ultrasound-guided pulsed radiofrequency and hyaluronidase hydrodissection in the treatment of carpal tunnel syndrome. This research seeks to evaluate both techniques in terms of pain relief, functional improvement, nerve conduction parameters, and potential complications, in order to identify the more effective minimally invasive approach for managing carpal tunnel syndrome.

Inclusion Criteria:

1. Adults aged 20-80 years
2. Clinical diagnosis of CTS with symptoms for at least 3 months
3. Electrophysiological evidence of mild to moderate CTS
4. No previous intervention for CTS in the affected hand

Exclusion Criteria:

1. Previous wrist surgery or trauma
2. Medical history of polyneuropathy, thoracic outlet syndrome, or brachial plexopathy
3. Coagulopathy or local infection at injection site
4. Pregnancy or breastfeeding