No local data exists regarding the outcomes of anterior cruciate ligament reconstruction by hamstring graft with and without platelet-rich plasma. This study aimed to compare the functional outcomes of arthroscopic anterior cruciate ligament reconstruction by hamstring graft with and without platelet-rich plasma.

In animal studies, platelet-rich plasma has shown excellent results in accelerating the healing of the anterior cruciate ligament, but studies on human have shown varying clinical outcomes when investigating platelet-rich plasma for its effects on anterior cruciate ligament reconstruction. The findings of this study could provide important insights about the possible role of platelet-rich plasma in arthroscopic anterior cruciate ligament reconstruction by hamstring graft. to enhance early graft healing and reduce early complications, though its long-term effectiveness remains inconsistent. Studies suggest PRP may improve short-to-medium term outcomes like reduced pain and enhanced knee function,

Inclusion Criteria:

• Any gender
• Aged 18-40 years
• With clinically and radiologically confirmed arthroscopic evidence of ACL injury

Exclusion Criteria:

• With comprised bilateral ACL tears
• Lack of fitness due to associated comorbidity
• Fractures of lower limb bones and/or spine/neurovascular injuries
• Injuries to other knee ligaments
• Significant knee joint arthritis
• Local skin infections

Data can be shared on a reasonable request.