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This study investigates the effects of jackfruit oil extract on adipokine levels (Irisin, Omentin-1), brain-derived neurotrophic factor (BDNF), cognitive performance, and body measurements in healthy young boxers aged 18-25. Participants were randomly assigned to four groups receiving different doses of jackfruit oil extract (0, 100, 200, 300 mg/kg) or no supplement. Saliva samples, cognitive tests, and body measurements were collected at the start of the study and after 30 days to evaluate the outcomes.
This interventional study evaluates the effects of different doses of jackfruit oil extract on healthy young boxers aged 18-25. Participants were randomly assigned to four groups and followed for 30 days.
Saliva samples were collected to measure irisin, omentin-1, and BDNF levels. Cognitive performance was assessed using the Wisconsin Card Sorting Test and the Trail Making Test. Anthropometric parameters including weight, BMI, waist, hip, chest, limb circumferences, and body composition were measured at baseline and on day 30.
Statistical analyses were performed using SPSS version 26. ANOVA, Duncan, and Pearson correlation tests were used to determine significant differences and relationships between variables.
This study is randomized and controlled. Participants receive either one of three doses of jackfruit oil extract or no supplement. The follow-up period is 30 days.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| J0 - Kontrol Grubu | No Intervention | Katılımcılar hiçbir jackfruit yağı ekstresi almadı. Sadece normal diyet ve antrenman programlarını sürdürdüler. | |
| J100 | Experimental | Katılımcılara 100 mg/kg jackfruit yağı ekstresi oral olarak 500 ml su içinde verildi. Müdahale 30 gün boyunca günlük olarak uygulandı. |
|
| J200 | Experimental | Katılımcılara 200 mg/kg jackfruit yağı ekstresi oral olarak 500 ml su içinde verildi. Müdahale 30 gün boyunca günlük olarak uygulandı. |
|
| J300 | Experimental | Katılımcılara 300 mg/kg jackfruit yağı ekstresi oral olarak 500 ml su içinde verildi. Müdahale 30 gün boyunca günlük olarak uygulandı. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Jackfruit Supplement | Dietary Supplement | Participants in the experimental group will receive a daily dose of jackfruit supplement during the study period. The supplement is administered orally and standardized for bioactive components. Participants in the control group will not receive any jackfruit supplement. |
| Measure | Description | Time Frame |
|---|---|---|
| Salivary Irisin Level | Irisin levels measured from saliva samples collected from participants using the ELISA method. | Day 0 and Day 30 |
| Salivary Omentin-1 Level | Omentin-1 levels measured from saliva samples collected from participants using the ELISA method. | Day 0 and Day 30. |
| Salivary BDNF Level | BDNF levels measured from saliva samples collected from participants using the ELISA method. | Day 0 and Day 30. |
| Measure | Description | Time Frame |
|---|---|---|
| Body Weight (kg) | Body weight measured using Tanita BC-418 bioimpedance device. | Day 0 and Day 30 |
| Height (cm) | Height measured using a standard stadiometer. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| BÜLENT BAYRAKTAR | BAYBURT ÜNİVERSİTESİ | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bayburt Gençlik Merkezi Kapali Spor Salonu | Bayburt | Merkez | 69000 | Turkey (Türkiye) |
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| Label | URL |
|---|---|
| This study investigates the effects of jackfruit consumption on adipokine levels (irisin, omentin-1), brain-derived neurotrophic factor (BDNF), cognitive performance, and anthropometric parameters in young boxers aged 18-25. | View source |
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De-identified participant-level data including salivary irisin, omentin-1, BDNF levels, anthropometric measurements, and cognitive test results will be shared with other researchers upon reasonable request after publication of the main study results. Access will require approval from the institutional ethics committee and signing a data use agreement.
De-identified participant-level data and supporting documents will be available to other researchers starting after publication of the main study results and will remain accessible for 5 years following publication.
"Access to de-identified participant-level data and supporting documents will be granted to qualified researchers for legitimate scientific purposes. Researchers must submit a request detailing their research objectives and methods, obtain approval from the institutional ethics committee, and sign a data use agreement. Approved researchers will receive access to the specified datasets and supporting materials electronically.
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Participants were randomly assigned to four parallel groups (J0, J100, J200, J300) receiving different doses of jackfruit oil extract (0, 100, 200, 300 mg/kg). Each group received the assigned intervention for 30 days, and outcomes including salivary irisin, omentin-1, BDNF levels, cognitive performance, and anthropometric measurements were assessed at baseline and at the end of the intervention.
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| Day 0 and Day 30 |
| Body Mass Index (kg/m²) | BMI calculated using the formula weight (kg)/height (m²). | Day 0 and Day 30 |
| Waist Circumference (cm) | Waist circumference measured with a flexible tape measure. | Day 0 and Day 30 |
| Hip Circumference (cm) | Hip circumference measured with a flexible tape measure. | Day 0 and Day 30 |
| Chest Circumference (cm) | Chest circumference measured using a flexible tape measure. | Day 0 and Day 30 |
| Upper Arm Circumference (Right/Left, cm) | Right and left upper arm circumferences measured with a flexible tape measure. | Day 0 and Day 30 |
| Wrist Circumference (Right/Left, cm) | Right and left wrist circumferences measured with a flexible tape measure. | Day 0 and Day 30 |
| Thigh Circumference (Right/Left, cm) | Right and left thigh circumferences measured with a flexible tape measure. | Day 0 and Day 30 |
| Calf Circumference (Right/Left, cm) | Right and left calf circumferences measured with a flexible tape measure. | Day 0 and Day 30 |
| Total Body Fat Mass (kg) | Total body fat mass measured using Tanita BC-418. | Day 0 and Day 30 |
| Total Body Fat Percentage (%) | Total body fat percentage measured using Tanita BC-418. | Day 0 and Day 30 |
| Abdominal Fat Mass (kg) | Abdominal fat mass measured using Tanita BC-418. | Day 0 and Day 30 |
| Regional Fat Percentages (Right/Left Arm & Leg) | Regional fat percentages for arms and legs measured by Tanita BC-418. | Day 0 and Day 30 |
| Total Muscle Mass (kg) | Total muscle mass assessed using Tanita BC-418. | Day 0 and Day 30 |
| Regional Muscle Mass (Right/Left Arm & Leg, kg) | Regional muscle mass of arms and legs measured by Tanita BC-418. | Day 0 and Day 30 |
| Basal Metabolic Rate (BMR) | Basal metabolic rate calculated by Tanita BC-418. | Day 0 and Day 30 |
| Metabolic Age | Metabolic age estimated using Tanita BC-418 device. | Day 0 and Day 30 |
| Total Body Water (kg) | Total body water measured via bioimpedance analysis. | Day 0 and Day 30 |
| Total Body Water Percentage (%) | Total Body Water Percentage (%) | Day 0 and Day 30 |
| WCST Total Correct Responses | Total correct responses obtained from the Wisconsin Card Sorting Test. | Day 0 and Day 30 |
| WCST Total Incorrect Responses | Total incorrect responses measured using the Wisconsin Card Sorting Test. | Day 0 and Day 30 |
| WCST Perseverative Error Count | Perseverative errors recorded during the Wisconsin Card Sorting Test. | Day 0 and Day 30 |
| WCST Total Time (seconds) | Total time required to complete the Wisconsin Card Sorting Test. | Day 0 and Day 30 |
| Trail Making Test A Completion Time (seconds) | Completion time for Trail Making Test Part A. | Day 0 and Day 30 |
| Trail Making Test B Completion Time (seconds) | Completion time for Trail Making Test Part B. | Day 0 and Day 30 |
| Biomarker Correlations (Irisin-Omentin-BDNF vs. Dose/Day) | Pearson correlation analysis examining relationships between biomarkers and intervention dose/day. | Based on Day 30 measurements |
| Safety Outcomes (Adverse Event Monitoring) | Monitoring of potential adverse events related to 300 mg/kg JOE administration. | Continuous monitoring throughout 30 days |