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Liver Transplantation (LT) is a lifesaving intervention with around 90% of recipients currently surviving the first postoperative year and subsequent life expectancy now exceeding 20 years. After the post-operative recovery period, however, LT recipients become more and more confronted with the challenges of re-engagement with life after transplantation, a need to reach a new stability, reestablish function in everyday life, reconnect with valued roles, regain independence, and resume work Sexual function is a very important parameter in the evaluation of Quality of Life (QoL), as it has been shown that sexual dysfunction in transplant patients is associated with increased depression and decreased QoL. There are several studies in the relevant literature supporting the recovery of sexual function in patients after liver transplantation. It has been found that recovery was observed in erectile dysfunction in male patients 6 months after liver transplantation.
Liver Transplantation (LT) is a lifesaving intervention with around 90% of recipients currently surviving the first postoperative year and subsequent life expectancy now exceeding 20 years. After the post-operative recovery period, however, LT recipients become more and more confronted with the challenges of re-engagement with life after transplantation, a need to reach a new stability, reestablish function in everyday life, reconnect with valued roles, regain independence, and resume work Sexual function is a very important parameter in the evaluation of Quality of Life (QoL), as it has been shown that sexual dysfunction in transplant patients is associated with increased depression and decreased QoL. There are several studies in the relevant literature supporting the recovery of sexual function in patients after liver transplantation. It has been found that recovery was observed in erectile dysfunction in male patients 6 months after LT
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Chronic liver Disease | Chronic Liver disease patients undergoing elective liver transplantation |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| No Treatment | Other | This is an Observational Study |
|
| Measure | Description | Time Frame |
|---|---|---|
| Evaluation of sexual function by questionnaire method | Arizona Sexual Experience Scale (ASEX) scores for sexual dysfunction, ASEX scores are 5 point questionnaire with scores given for each question from 1-6. Total scores More than or equal to 19 indicate sexual dysfunction (higher the scores greater the sexual dysfunction). | pre transplant, 3,6,12 months |
| Evaluation of erectile dysfunction using questionnaire method | International Index for Erectile Function - 5 (IIEF-5) scores for erectile dysfunction IIEF 5 scores are also a 5 point questionnaire with score ranging 0-6 for each question. Total scores less than 15 indicate mild to moderate erectile dusfunction and scores less than 11 indicate moderate erectile dysfunction (lower the scores higher the erectile dysfunction) | pre transplant, 3,6,12 months |
| Measure | Description | Time Frame |
|---|---|---|
| Correlation between testosterone and Meld Na scores | Testosterone measured in ng/ml. Less than 2.84 ng/ml is considered as hypogonadism | pre transplant, 3,6,12 months |
| Sarcopenia implication in recovery of sexual function. |
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Inclusion Criteria:
Exclusion Criteria:
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Chronic Liver Disease patients awaiting elective transplantation and post liver transplant patients.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Dr. Rajagopalan G, DNB | Contact | 8220408324 | prash1108@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Prof. Dr. Viniyendra Pamecha, MS FEBS | ILBS | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| ILBS | Recruiting | New Delhi | National Capital Territory of Delhi | 110070 | India |
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| ID | Term |
|---|---|
| D005355 | Fibrosis |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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Sarcopenia measured by third lumbar vertebra Skeletal muscle index. Values less than 52 indicates sarcopenia
| pre transplant, 3,6,12 months |