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| Name | Class |
|---|---|
| China-Japan Union Hospital, Jilin University | OTHER |
Following thorough screening based on inclusion and exclusion criteria, patients from the two sizable medical centers were split up into two cohorts for this study. Cohort 1 served primarily as the training and internal validation set, while Cohort 2 was used for external validation of the predictive model constructed from Cohort 1. We used six distinct machine learning methodss, including DT, RF, XGBOOST, SVM, lightGBM, and SHLNN, in addition to conventional logistic regression to create the predictive model. We chose the approach with the best sensitivity and specificity by comparing the concordance index(C-index) akin to the area under the ROC curve (AUC) of these seven distinct model-building methods. The predictive model for Cohort 1 was then built using this method, and internal validation was finished. Lastly, Cohort 2 underwent external validation of the predictive model
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| nCRT | Procedure | neoadjuvant chemoradiotherapy | ||
| BMI | Behavioral | Body Mass Index | ||
| Distance from AV | Diagnostic Test | Distance from AV | ||
| Surgical type | Procedure | laparoscopic and robotic surgery | ||
| Surgical approach | Procedure | tatme + isr | ||
| LCA Preserving | Procedure | LCA Preserving |
| Measure | Description | Time Frame |
|---|---|---|
| low anterior resection syndrome | 1 and 3 months after surgery | |
| Comparison of Six Different Machine Learning Methods With Traditional Model for Low Anterior Resection Syndrome After Minimally Invasive Surgery for Rectal Cancer -- Development and External Validation of a Nomogram : A Dual-center Cohort Study | using LARS Score to assess the LARS situation | 3 months |
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Inclusion Criteria:(1) rectal adenocarcinoma (2) minimally invasive sphincter-preserving surgery (taTME/ISR/LAR) (3) intact baseline anal function (4) no emergent presentations or metastases.
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Exclusion Criteria:emergent presentations or metastases
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This retrospective analysis included 3,937 radical rectal cancer cases from two Chinese university hospitals (Northern Jiangsu People's Hospital 2015-2023, n=2612; Jilin University's China-Japan Union Hospital 2021-2023, n=1325), with rigorous selection criteria ensuring cohort homogeneity
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| Prophylactic stoma | Procedure | Prophylactic stoma |
| Anastomotic leakage | Procedure | Anastomotic leakage |
| ID | Term |
|---|---|
| D012004 | Rectal Neoplasms |
| D000094123 | Low Anterior Resection Syndrome |
| ID | Term |
|---|---|
| D015179 | Colorectal Neoplasms |
| D007414 | Intestinal Neoplasms |
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D004066 | Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D007410 | Intestinal Diseases |
| D012002 | Rectal Diseases |
| D003108 | Colonic Diseases |
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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