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Stroke is a leading cause of acquired motor disability and the second most common cause of major cognitive impairment worldwide. In France, approximately 150,000 new cases occur annually, with around 31% affecting individuals of working age, making return to work (RTW) a critical public health issue. Beyond the medical burden, stroke has profound socio-economic consequences, including loss of productivity, prolonged sick leave, part-time resumption, and the need for workplace adaptations. While RTW after stroke has been investigated, major gaps remain. No standardized recommendations exist for vocational reintegration, and predictive factors are still debated. Quantitative determinants such as stroke type, severity, functional independence, and occupational characteristics have been identified, but qualitative aspects-including self-efficacy, perceived social burden, employer relationships, and motivation-are poorly documented. Moreover, cognitive deficits are often insufficiently characterized, as screening tools such as MMSE or MoCA lack the sensitivity of comprehensive neuropsychological assessments. The impact of revascularization procedures on RTW and the ability to sustain employment after initial resumption also remain unclear. Importantly, no recent data are available in the Auvergne region, despite evolving labor policies that may influence reintegration trajectories. This observational study therefore aims to identify both quantitative and qualitative predictors of RTW after ischemic or hemorrhagic stroke, describe vocational pathways in a regional cohort, and explore barriers and facilitators to long-term reintegration. Ultimately, the study seeks to provide updated evidence to guide tailored rehabilitation and socio-professional reintegration strategies, supporting sustainable RTW in working-age stroke survivors.
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| Measure | Description | Time Frame |
|---|---|---|
| Return to work rate | Percentage of return to work after a first ischaemic or haemorrhagic stroke between January 2020 and December 2024 in patients of working age. | At inclusion |
| Factors correlated with return to work | Determine the factors associated with return to work (gender) | At inclusion |
| Factors correlated with return to work | Determine the factors associated with return to work (stroke severity) | At inclusion |
| Factors correlated with return to work | Determine the factors associated with return to work (stroke type (ischaemic or haemorrhagic)). | At inclusion |
| Factors correlated with return to work | Determine the factors associated with return to work (independence) | At inclusion |
| Factors correlated with return to work | Determine the factors associated with return to work (occupation) | At inclusion |
| Measure | Description | Time Frame |
|---|---|---|
| Quality of life after stroke | The Short-Form-12 (SF-12) questionnaire is a standardized self-administered questionnaire used to assess health-related quality of life. It comprises 12 questions covering 8 domains: physical activities, physical and mental limitations, pain, perceived general health, vitality, mental health and social relationships. Each item is rated on a 5- or 6-point Likert scale. The responses are used to calculate two scores: a physical composite score (PCS) and a mental composite score (MCS), each ranging from 0 (perceived health status very poor) to 100 (perceived health status optimal). |
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Inclusion Criteria:
Exclusion Criteria:
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Stroke management follows a continuum, starting with acute care in neurology and neurosurgery, then progressing to medium- and long-term multidisciplinary rehabilitation in the Physical Medicine and Rehabilitation (PMR) department of Clermont-Ferrand University Hospital. Within this context, return to work is a key objective, supported by the expertise of PMR teams and close collaboration with neurology and neurosurgery. To conduct this study, authorisation to access medical records was granted by the Medical Information Department (DIM), covering patients under 64 years old admitted for ischaemic or haemorrhagic stroke between January 2020 and December 2024. Screening will be performed on hospitalisations in neurology and neurosurgery, and all eligible patients experiencing a first stroke during this period will be invited to participate.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Lise Laclautre | Contact | +33473754963 | promo_interne_drci@chu-clermontferrand.fr |
| Name | Affiliation | Role |
|---|---|---|
| Lise Laclautre | University Hospital, Clermont-Ferrand | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Clermont Ferrand University Hospital, Louise Michel site | Recruiting | Cébazat | France | 63118 | France | |
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| At inclusion |
| Anxiety and Depression scale | The Hospital Anxiety and Depression Scale (HADs) questionnaire is a psychometric self-assessment questionnaire consisting of 14 items divided into two subscales (anxiety and depression) of seven items each. Each item is rated on a scale of 0 to 3. A score is given for each subscale, A for anxiety and D for depression. The score can range from 0 (no anxiety and/or depressive disorders) to 21 (proven anxiety and/or depressive disorders of varying severity) for each subscale. | At inclusion |
| Fatigue Severity Scale | The Fatigue Severity Scale (FSS) questionnaire is a self-assessment tool used to evaluate the severity of fatigue and its impact on daily activities. This questionnaire consists of nine items rated on a seven-point Likert scale, ranging from 1 ('strongly disagree') to 7 ('strongly agree'). The score ranges from 7 (no fatigue in daily activities) to 63 (extreme fatigue in daily activities). A score above 36 indicates that the patient may need to have their fatigue assessed by a healthcare professional. | At inclusion |
| Predictive score for return-to-work rate | Develop a predictive score for return to work using the predictive factors for return to work identified in the main objective. | At inclusion |
| Job retention | To study job retention and its association with factors such as stroke severity. | At inclusion |
| CHU Clermont-Ferrand, Louise Michel |
| Not yet recruiting |
| Clermont-Ferrand |
| France |
|
| ID | Term |
|---|---|
| D020521 | Stroke |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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