Comparison of Peak Expiratory Flow Changes After Robot-Assisted Versus Open Radical Prostatectomy

Prospective Randomized Controlled Study Comparing Peak Expiratory Flow (PEF) Changes After Robot-Assisted and Open Radical Prostatectomy

This prospective, randomized controlled trial aims to compare perioperative respiratory changes in patients undergoing robot-assisted laparoscopic radical prostatectomy (RALRP) and open radical prostatectomy (ORP). The primary outcome is the change in peak expiratory flow (PEF) from the preoperative period to the early postoperative (2nd hour) period. Secondary outcomes include PEF recovery at 24 hours, and correlations between PEF change and intraoperative factors such as Trendelenburg angle, pneumoperitoneum duration, and ventilatory parameters.

Inclusion Criteria:

• Male, 18-80 years old
• ASA physical status I-III
• Scheduled for open or robot-assisted radical prostatectomy
• Able to provide informed consent and follow Turkish instructions

Exclusion Criteria:

• Moderate/severe COPD (GOLD II-IV)
• Active upper respiratory tract infection
• Severe OSA requiring CPAP
• Inability to perform standardized PEF maneuver
• Emergency surgery
• Cognitive impairment preventing participation