Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
In 2015 ObGyn Dept of Santo Spirito Hospital in Pescara (Italy) started protocol for previous CS vaginal birth. In 2021 was started a protocol for training on obstetric emergencies and protocol on two previous cesarean was endorsed. Patients attending birth in Pescara with two previous from january 2016 to December 2020, and from january 2021 to december 2025 were collected. A different counseling approach was adopted from 2021. Women's acceptance of trial of labor and maternal and fetal outcomes were collected.
Women attending birth in Santo Spirito Hospital with 2 previous CS were collected.
Exclusion Criteria:
Primary outcomes:
Secondary outcomes:
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group 2 | term pregnant women with 2 previous CS from 01.01.2021 to 31.12.2025 |
| |
| Group 1 | Women with a history of two previous CS in period 01.01.2026 - 31-12.2020 |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Acceptance, rate of vaginal birth and safety | Procedure | In 2021 started a new delivery protocol enhancing the opportunity of having a trial of labor in women with a history of two previous CS. Rate of acceptance, rate of successful vaginal birth, maternal and fetal outcomes were evaluated |
| Measure | Description | Time Frame |
|---|---|---|
| vaginal birth after 2 cesarean | Incidence of patients having a vaginal birth after 2 CS | 5 years |
| accepted indication to trial of labor | incidence of women accepting indication to trial of labor | 5 years |
| Measure | Description | Time Frame |
|---|---|---|
| emergency CS | incidence of emergency CS | 5 years |
| maternal outcomes | incidence of adverse maternal outcomes (PPH, blood transfusion, vaginal tears, hysterectomy) |
Not provided
Inclusion Criteria:
Exclusion Criteria:
pregnant women
Not provided
pregnant women attending birth in Santo Spirito Hospital Pescara (Italy) from 01-01-2016 to 31-12-2025
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Claudio Celentano, MD | Contact | +39 328 5577305 | celentanoclaudio70@gmail.com |
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Claudio Celentano | Recruiting | Pescara | PE | 65100 | Italy |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40771829 | Result | Brandstetter M, Brandstetter A, Kainz-Schultes S, Jacobs VR, Fazelnia C, Fischer T, Bogner G. Successful Trial of Labor After Two Caesarean Sections (TOLA2C): Analysis of a Delivery Protocol with Feto-Maternal Outcome. Geburtshilfe Frauenheilkd. 2025 Feb 7;85(8):862-869. doi: 10.1055/a-2513-6562. eCollection 2025 Aug. |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D012449 | Safety |
| ID | Term |
|---|---|
| D000056 | Accident Prevention |
| D000059 | Accidents |
| D011634 | Public Health |
| D004778 | Environment and Public Health |
Not provided
Not provided
Not provided
Not provided
Not provided
|
| 5 years |
| Fetal and Neonatal adverse outcomes | Incidence of fetal/neonatal death, NICU stay, APGAR score below 7 at 5' | 5 years |
| Santo Spirito Hospital | Recruiting | Pescara | PE | 65123 | Italy |
|