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| ID | Type | Description | Link |
|---|---|---|---|
| MACREB-BPIT-2025-014 | Other Identifier | nstitutional Ethics Committee Approval Number (MMSx Authority / GFFI Ethics Committee) |
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| Name | Class |
|---|---|
| BodyGNTX Fitness Institute | UNKNOWN |
| GFFI Fitness Academy | UNKNOWN |
| Indian Institute of Kinesiology and Biomechanics Science (IIKBS) | UNKNOWN |
| Bureau of Fitness Standards (BFS) |
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This prospective, multi-site, single-arm interventional study evaluates the 5-Line Principle of Balanced Progressive Intensity Training (BPIT) over 5 weeks in healthy adults aged 18-65 years. All participants receive supervised BPIT sessions (3-5 per week) progressing through five intensity lines defined by anatomical landmarks and ground reaction force:
Ground-Based (Low) Knee-Level (Low-Moderate) Standing (Moderate) Head-Level (Moderate-High) Plyometric (High-Impact)
The study aims to quantify improvements in functional movement efficiency, joint mobility, postural control, strength adaptation, and heart-rate variability while monitoring safety and individual overload indicators.
Primary Outcome Measures
Change in Functional Movement Screen (FMS) total score from baseline to Week 5 Change in Y-Balance Test reach distance (composite score) Timeframe: Baseline and Week 5
Secondary Outcome Measures
Change in 1-RM or estimated strength (squat, deadlift, overhead press) Change in resting HRV (RMSSD) Change in joint range of motion (goniometry) and postural sway Incidence of training-related discomfort or minor injury Timeframe: Baseline, weekly, and Week 5
Arms/Intervention Experimental: BPIT 5-Line Training Group Intervention: Behavioral: Balanced Progressive Intensity Training (BPIT) 5-Line Method Description: 5-week supervised progressive training using the BPIT 5-Line framework (ground-based → plyometric) Eligibility
Ages Eligible: 18 Years to 65 Years Sexes Eligible: All Accepts Healthy Volunteers: Yes
Inclusion Criteria
Healthy adults with regular exercise history Able to attend 3-5 training sessions/week Signed informed consent
Exclusion Criteria
Recent injury (<3 months) Known cardiovascular, metabolic, or orthopaedic contraindications Pregnancy
Study Locations 13 Locations in India 2 Locations in USA, (Details of the location is uploaded on mmsxauthority.com webiste)
MMSx Authority , USA, GFFI Fitness Academy, New Delhi BodyGNTX USA BFS/AIHFT-approved facilities
Countries of Recruitment India U.S. FDA-regulated? No / No / No Human Subjects Protection Review Board Status Approved (or Submit for review if not yet) Board Name: Institutional Ethics Committee - MMSx Authority / GFFI Approval Number: BPIT-MULTI-2025-001 (or pending) Data Monitoring Committee No
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| BPIT 5-Line Training Group | Experimental | All participants receive the 5-week Balanced Progressive Intensity Training (BPIT) program using the 5-Line Principle (ground-based → knee-level → standing → head-level → plyometric) under supervised sessions 3-5 times per week. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Balanced Progressive Intensity Training (BPIT) 5-Line Method | Behavioral | 5-week supervised progressive training using the BPIT 5-Line framework developed by Dr. Neeraj Mehta. |
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| Measure | Description | Time Frame |
|---|---|---|
| Movement Efficiency Score (MES, 0-10) | Change from baseline in the proprietary Movement Efficiency Score (MES), a validated composite metric of biomechanical function, movement quality, and postural alignment (derived from MMSx Flaw Checklist, visual/video analysis, and functional mapping). | Baseline (Week 0) and end of study (Week 5) |
| Measure | Description | Time Frame |
|---|---|---|
| Range of Motion (ROM) | Change from baseline in joint range of motion (degrees) measured by goniometry at key sites (shoulder, hip, spine, ankle). | Baseline and Week 5 |
| VAS Pain Score | Change from baseline in participant-reported pain/discomfort on a 0-10 Visual Analog Scale. |
| Measure | Description | Time Frame |
|---|---|---|
| Heart Rate Variability (HRV - RMSSD) | Change from baseline in resting heart rate variability (RMSSD) as a biomarker of autonomic recovery. | Baseline and Week 5 |
Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| BodyGNTX Fitness Institute | Recruiting | Columbus | Ohio | 43220 | United States |
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot | Yes | No | No | Study Protocol | Dec 8, 2025 | Dec 8, 2025 |
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| UNKNOWN |
| Active India Health & Fitness Trust (AIHFT) | UNKNOWN |
| Body Mechanic Chain of Gyms | UNKNOWN |
| Shri Mahaveer Ortho Clinic | UNKNOWN |
| Regain Fitness Zone | UNKNOWN |
| MMSx Authority Biomechanics Department | UNKNOWN |
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Single-arm prospective interventional study
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| Baseline and Week 5 |
| Strength Index | Change from baseline in Strength Index calculated as Reps × Load (or estimated 1RM where applicable) for key movements. | Baseline and Week 5 |
| Mobility Limitation (%) | Change from baseline in self-reported percentage limitation in daily functional tasks due to mobility restrictions. | Baseline and Week 5 |
| MMSx Authority Biomechanics Department | Recruiting | Powell | Ohio | 43065 | United States |
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| MMSx AUTHORITY INSTITUTE FOR MOVEMENT MECHANICS & BIOMECHANICS RESEARCH (COORDINATING CENTER) | Recruiting | Powell | Ohio | 43065 | United States |
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| Indian Institute of Kinesiology & Biomechanics Science (IIKBS) | Recruiting | Burhānpur | Madhya Pradesh | 450331 | India |
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| Shri Mahaveer Ortho Clinic | Recruiting | Delhi | National Capital Territory of Delhi | 110032 | India |
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| GFFI Fitness Academy | Recruiting | New Delhi | National Capital Territory of Delhi | 110026 | India |
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| Active India Health & Fitness Trust (AIHFT) | Recruiting | New Delhi | National Capital Territory of Delhi | 110063 | India |
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| Body Mechanics Gym P Ltd | Recruiting | New Delhi | National Capital Territory of Delhi | 110092 | India |
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| Regain Fitness Zone | Recruiting | Greater Noida | Uttar Pardesh | 201310 | India |
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| GFFI Fitness Academy | Recruiting | Agra | Uttar Pradesh | 282005 | India |
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| Prot_003.pdf |
| SAP | No | Yes | No | Statistical Analysis Plan | Nov 25, 2025 | Nov 25, 2025 | SAP_001.pdf |
| ICF | No | No | Yes | Informed Consent Form | Nov 24, 2025 | Nov 25, 2025 | ICF_002.pdf |