Accuracy Between Transthoracal Needle Aspiration (TTNA) Techniques in Suspected Lung Cancer Patients

Accuracy Between Jabbing-then-suction, Suction-with-jabbing, and Suction-only Transthoracal Needle Aspiration (TTNA) Techniques in Suspected Lung Cancer Patients

• The objective of this research is to determine the accuracy of different types of lung transthoracal needle aspiration (TTNA) i.e. jabbing-then-suction, suction-with-jabbing, and suction-only TTNA in patients with suspected lung cancer.
• Researchers will compare these techniques to determine whether there are any quality differences in the obtained tumor samples

During hospitalization for diagnostic testing, suspected lung cancer patients will undergo a transthoracic biopsy using three TTNA techniques, and core needle biopsy as the gold standard. The biopsy is performed in the operating room under local anesthesia and under the supervision of an anesthesiologist. The biopsy techniques used are routine procedures and therefore not as a new method. After the biopsy is completed, the patient is observed for at least 24 hours to observe potential complications.

Inclusion Criteria:

• Patients with suspected lung cancer who will undergo diagnostic testing using ultrasound-guided TTNA of the lung with cell block and core biopsy.
• Patients aged 18-75 years.
• The tumor is located peripherally, attached to the chest wall.

Exclusion Criteria:

• Patient refuses lung biopsy
• Non-cooperative patient
• Patient with respiratory failure, on positive pressure ventilation
• Severe pulmonary emphysema
• Contralateral pneumonectomy
• Advanced pulmonary fibrosis
• Platelet count <100,000/mm3 and international normalized ratio (INR) >1.4