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This is a prospective, blinded, single-center, randomized controlled trial. Investigators will include 208 patients with postoperative urinary retention (POUR) after radical hysterectomy for cervical cancer who have a clear diagnosis and meet the screening criteria. Participants will be randomly divided into the electroacupuncture（EA）group and the sham EA group according to a 1:1 ratio. Each group consists of 104 patients, and all participants will be required to sign a written informed consent form. The TEAS group will be treated with EA based on conventional treatment, and the shamEA group will be treated with sham EA based on conventional treatment. The main outcomes will be to calculate the proportion of patients who successfully removed the urinary catheter, and the secondary indicators will include the change in post-void residual (PVR) volume of the bladder, assessment of urinary tract infection (UTI), and quality of life assessment according to the EORTC QLQ-C30 scale. Evaluation of participant-reported expectations, blinding, compliance, and safety will also be conducted. All analyses will be conducted in accordance with the intention-to-treat principle.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| The EA Group | Experimental | Participants will receive the EA intervention for two consecutive weeks. |
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| The sham EA Group | Sham Comparator | Participants will receive the sham EA intervention for two consecutive weeks. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| EA intervention | Other | Participants will undergo EA treatment. Acupoint selection: Shenshu(BL23), Pangguanghu (BL28), Ciliao (BL32), Zhongliao (BL33), Huiyang (BL35), and Zhibian (BL54). Acupuncture needles (0.30 × 50 mm) will be vertically inserted into BL32, BL23, BL28, and BL35 at a depth of 40 ± 8 mm. The disposable acupuncture needle (0.45 × 75 mm) will be inserted into BL54 at a depth of 55 ± 10 mm, with the direction of insertion toward Shuidao (ST28). EA will be applied to the BL32 and BL54 points on both sides of the spine at a frequency of 2 Hz and a stimulation intensity of 2 ± 1.5 mA. Each treatment will last for 30 minutes, 5 days per week, for 2 weeks. Follow-up will be performed 2 weeks after the final treatment. |
| Measure | Description | Time Frame |
|---|---|---|
| The response rate of participants who will successfully remove the urinary catheter | The participants in each group who will remove their urinary catheters after intervention, in proportion to the total number of patients in each group, multiplied by 100%. It can also be understood as the initial cure rate of POUR. The standard for patients to remove the urinary catheter is that the PVR volume is less than 100ml. | week 0（baseline），and week 2 (after intervention) |
| Measure | Description | Time Frame |
|---|---|---|
| The changes in PVR volume. | It will be measured by professional nurses, using a direct measurement method. | week 0 (baseline), week 2 (after intervention), and week 4 （follow-up） |
| Assessment of UTI. |
| Measure | Description | Time Frame |
|---|---|---|
| Expectation evaluation | Evaluation of Participants' Expectations. It can be understood as the proportion of participants who expect effective, ineffective, or unclear treatment outcomes. | week 0 (baseline) |
| Blinding evaluation |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Chao Lu | Contact | 15869128904 | 1069103617@qq.com |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41878088 | Derived | Lu C, Chen N, Sun H, Wang C, Zhao L, Bao W, Deng D, Wang P, Li X. Effect of Electroacupuncture on Postoperative Urinary Retention After Radical Hysterectomy for Cervical Cancer: Study Protocol for A Randomized Controlled Trial. J Pain Res. 2026 Mar 18;19:598960. doi: 10.2147/JPR.S598960. eCollection 2026. |
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| Sham EA intervention | Other | Participants will receive sham EA treatment. Acupoint selection: consistent with the EA group. Sham acupuncture procedure: The disposable acupuncture needle (0.25 × 40 mm) will be used, and all acupoints will be shallowly penetrated into the skin using a vertical method, with a needle depth of 5 ± 2 mm. Sham EA application: EA electrodes will be attached identically to the EA group at a frequency of 2 Hz and a nominal intensity of 2 mA. However, no electrical current will be delivered via the EA device, as the connecting wires will undergo specialized modification. Each treatment session will also last 30 minutes, 5 days per week, for 2 weeks. The Follow-up will also be performed 2 weeks after the final treatment. |
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Urinalysis or urine culture will be performed confirm the presence or absence of UTI.
| week 0 (baseline), week 2 (after intervention), and week 4 （follow-up） |
| Assessment of patient quality of life. | Patient quality of life according to the EORTC QLQ-C30 scale. Higher scores on the functional subscales indicate better quality of life, whereas higher scores on the symptom subscales reflect more severe symptoms. | week 0 (baseline), week 2 (after intervention), and week 4 （follow-up） |
Blinding evaluation. It can be understood as the proportion of participants who are unaware of the intervention methods they have received.
| week 2 (after intervention) |
| Compliance evaluation | Compliance evaluation. It can be understood as the proportion of participants who complete the study. | week 2 (after intervention), and week 4 （follow-up） |
| Safety evaluation | Safety evaluation.The proportion of participants experiencing adverse events such as needle pain and subcutaneous hematoma. | week 2 (after intervention), and week 4 （follow-up） |