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Waiting for administrative approval to start study.
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The purpose of this research is to test how processing food can affect how one's body responds to it.
The purpose of this project is to address the current gap in research on ultra-processed foods (UPFs) and cardiometabolic health with a feeding study that addresses the limitations of previously conducted intervention studies in matching UPF- and unprocessed- foods intervention diets for diet quality, nutrient content, and food type. Therefore, the primary objective is to evaluate diets composed primarily of ultra-processed or less processed foods that meet dietary guidelines recommendations on chronic disease risk factors. More specifically, when Dietary Guidelines for Americans (DGA)-compliant diets comprised of mostly ultra-processed and unprocessed foods (per Nova) are fed to generally healthy participants, determine whether there is an impact on:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Low-processed DGA Diet | Experimental | Participants will be provided a Dietary Guidelines for Americans (DGA) compliant diet comprised of low-processed foods (Nova Categories 1-3) |
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| Ultra-processed DGA Diet | Experimental | Participants will be provided a Dietary Guidelines for Americans (DGA) compliant diet comprised primarily of ultra-processed foods (Nova Category 4) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Low-processed DGA Diet | Other | Participants will consume a DGA menu made up of low-processed foods over a 4-week period |
|
| Measure | Description | Time Frame |
|---|---|---|
| Mean difference in systolic and diastolic blood pressure from baseline | Mean difference in systolic and diastolic blood pressure from baseline | Week 0, Week 4 |
| Measure | Description | Time Frame |
|---|---|---|
| Mean difference in fasting glucose and fasting insulin concentrations from baseline | Mean difference in fasting glucose and fasting insulin concentrations from baseline | Week 0, Week 4 |
| Mean difference in fasting triglyceride concentrations from baseline |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Julie Hess, PhD | USDA Grand Forks Human Nutrition Research Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| USDA Grand Forks Human Nutrition Research Center | Grand Forks | North Dakota | 58203 | United States |
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| ID | Term |
|---|---|
| D050177 | Overweight |
| D009765 | Obesity |
| D006973 | Hypertension |
| ID | Term |
|---|---|
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
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| Ultra-processed DGA Diet | Other | Participants will consume a DGA menu primarily made up of ultra-processed foods over a 4-week period |
|
Mean difference in fasting triglyceride concentrations from baseline |
| Week 0, Week 4 |
| D012816 |
| Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |